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Odd stuff Flashcards

1
Q

What is the extrinsic pathway mechanism for apoptosis? What is the intrinsic pathway mechanism for apoptosis?

A

caspase 8 caspase 9, cytochrome c

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2
Q

What bundle of joy has the Maltese cross? What are we really similar too, the same tick carries this too?

A

Babesiosis Lyme Disease

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3
Q

What are the two terms: REduce the pathogenic organism counts to a safe level? Inactivate all microbes including spores?

A

Disinfect Sterilize

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4
Q

What type of equipment does the following? Pressurized steam at 120 degrees C, sporicidal, may not reliably inactivate prions

A

Autoclave

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5
Q

What type of equipment does the following? Denature proteins and disrupt cell membranes, not sporicidal Name 2

A

Alcohols and Chlorhexidine

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6
Q

What type of equipment does the following? Oxidizes and denatures proteins, sporicidal

A

Chlorine

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7
Q

What type of equipment does the following? Alkylating agent, sporicidial

A

Ethylene oxide

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8
Q

What type of equipment does the following? Free radical oxidation, sporicidal

A

Hydrogen Peroxide

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9
Q

What type of equipment does the following? Halogenation of DNA and RNA, and proteins, may not be sporicidal

A

Iodine and Iodophors

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10
Q

What type of equipment does the following? Impair permeability of cell membranes, not sporicidal

A

Quaternary Amines

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11
Q

What disease is mixed cryoglobulinemia associated with? Palpable purpura, weakness, arthralgias

A

Hep C

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12
Q

Von Hippel-Lindau disease Renal Cell Carcinoma What is the magic chromosome?

A

Chromosome 3

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13
Q

ADPKD (PKD2), achondroplasia Huntington Disease What is the magic chromosome?

A

Chromosome 4

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14
Q

Cri-du-chat syndrome Familial adenomatous polyposis (FAP) What is the magic chromosome?

A

Chromosome 5

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15
Q

Hemochromatosis (HFE) What is the magic chromosome?

A

Chromosome 6

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16
Q

Friedreich ataxia Tuberous Sclerosis (TSC1) What is the magic chromosome?

A

Chromosome 9

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17
Q

Wilms Tumor B globin defects (sickle cell disease, B-Thalassemia) MEN 1 What is the magic chromosome?

A

Chromosome 11

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18
Q

Patau Syndrome Wilson Disease Retinoblastoma BRCA2 What is the magic chromosome?

A

Chromosome 13

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19
Q

Prader-Willi Syndrome Angelman Syndrome Marfan Syndrome What is the magic chromosome?

A

Chromosome 15

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20
Q

ADPKD (PKD1) Alpha globin gene defects (alpha thalassemia) Tuberous Sclerosis (TSC2) What is the magic chromosome?

A

Chromosome 16

21
Q

Neurofibromatosis type 1 BRCA1 TP53 What is the magic chromosome?

A

Chromosome 17

22
Q

Edwards Syndrome What is the magic chromosome?

A

Chromosome 18

23
Q

Down Syndrome What is the magic chromosome?

A

Chromosome 21

24
Q

Neurofibromatosis Type 2, DiGeorge Syndrome What is the magic chromosome?

A

Chromosome 22

25
Q

Fragile X X-linked agammaglobulinemia Klinefelter Syndrome (XXY) What is the magic chromosome?

A

Chromosome X

26
Q

Digoxin binds to the Na/K pump What drug binds to the K channels, with the same intention as Digoxin?

A

Ouabain

27
Q

Williams Syndrome Cystic Fibrosis What is the magic chromosome?

A

Chromosome 7

28
Q

What is different mutations in the same locus produce the same phenotype?

A

Allelic Heterogeneity Beta Thalassemia

29
Q

What is the -ximab used for/from? i.e. Rituximab

A

Chimeric human-mouse monoclonal AB

30
Q

What is the -zumab used for/from? i.e. Bevacizumab

A

Humanized mouse monoclonal AB

31
Q

What is the -umab used for/from? i.e. Denosumab

A

Human monoclonal AB

32
Q

What is the -tinib used for/from?

A

Tyrosine kinase inhibitor

33
Q

What is the -zomib used for/from?

A

Proteasome inhibitor

34
Q

What is the -ciclib used for/from?

A

Cyclin-dependent kinase inhibitor

35
Q

What is the -cept ending used for?

A

TNF-alpha antagonist

36
Q

What is the -leukin used for?

A

Aldesleukin

37
Q

What is the -kinra used for?

A

Interluekin receptor Antagonist

38
Q

What does Adalimumab, certolizumab, golimumab, and infliximab go after?

A

TNF-alpha

39
Q

What does Daclizumab target?

A

CD25, used in M.S.

40
Q

What does Eculizumab target?

A

Complement protein C5

41
Q

What does Natalizumab target?

A

alpha-4- integrin

42
Q

What does Ustekinumab target?

A

IL-12/IL-23

43
Q

What does Abciximab target?

A

Platelet glycoproteins IIb/IIIa

44
Q

What does Denosumab target?

A

RANKL, this is the dinosaur holding the hand crank drill in sketchy

45
Q

What does Omalizumab target?

A

IgE, this is the limo in the parade anti-inflammatory sketchy

46
Q

What does Palivizumab target?

A

RSV F Protein

47
Q

What is Erlotinib used for?

A

EGFR tyrosine Kinase inhibitor, “Geoffery, British Earl” Non small cell lung carcinoma

48
Q

What is cetuximab used for?

A

antibody against EGFR, colon cancer, tux from the elephant in sketchy

49
Q

What is Imatinib used for?

A

Tyrosine kinase BCR-ABL, inhibitor, Philly chromosome, CML “broken bell”, “Imitation guy in sketchy”

Exit Notecards (29 decks)

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