Obesity: physiology Flashcards
1
Q
What molecule is produced by adipose tissue and acts on satiety centres in the hypothalamus and decreases appetite.
A
leptin
2
Q
What hormones does leptin stimulate the release of?
A
melanocyte-stimulating hormone (MSH)
corticotrophin-releasing hormone (CRH)
Low levels of leptin stimulates the release of neuropeptide Y (NPY)
3
Q
What is responsible for stimulating hunger?
A
ghrelin
4
Q
Where is ghrelin produced?
A
P/D1 cells lining the fundus of the stomach and epsilon cells of the pancreas
5
Q
Describe Ghrelin levels before and after meals
A
Ghrelin levels increase before meals and decrease after meals
