Cell surface proteins Flashcards
stem cells
CD34
T helper
CD4, TCR, CD3, CD28
cytotoxic T
CD8, TCR, CD3, CD28
Regulatory T cell
CD4, CD25, TCR, CD3, CD28
B cell
CD20, CD19, CD40, MHC II, B7
Macrophage
CD14, CD40, MHC II, B7
Natural Killer cell
CD16, CD56
MHC molecule that presents lipid molecules
CD1
Found on thymocytes, T cells, and some natural killer cells that acts as a ligand for CD58 and CD59 and is involved in signal transduction and cell adhesion
CD2
The signalling component of the T cell receptor (TCR) complex
CD3
Found on helper T cells.
Co-receptor for MHC class II
Used by HIV to enter T cells
CD4
Found in the majority of mantle cell lymphomas
CD5
Found on cytotoxic T cells.
Co-receptor for MHC class I
Found on a subset of myeloid dendritic cells
CD8
Cell surface marker for macrophages
CD14
Expressed on Reed-Sternberg cells (along with CD30)
CD15
Bind to the Fc portion of IgG antibodies
CD16
Receptor for Epstein-Barr virus
CD21
Interacts with B7 on antigen presenting cell as costimulation signal
CD28
Protein tyrosine phosphatase present on all leucocytes
CD45
Unique marker for natural killer cells
CD56
Acts as the FAS receptor, involved in apoptosis
CD95