Immune system cells

Question 1

Involved in the cell-mediated immune response
Recognises antigens presented by MHC class II molecules
Expresses CD4
Also expresses CD3, TCR & CD28
Major source of IL-2
Mediates acute and chronic organ rejection

Answer 1

T helper cells

Question 2

Involved in the cell-mediated immune response
Recognises antigens presented by MHC class I molecules
Induce apoptosis in virally infected and tumour cells
Expresses CD8
Also expresses CD3, TCR
Mediates acute and chronic organ rejection

Answer 2

Cytotoxic T cells

Question 3

Major cell of the humoral immune response
Acts as an antigen presenting cell
Mediates hyperacute organ rejection

Answer 3

B cells

Question 4

Differentiated from B cells
Produces large amounts of antibody specific to a particular antigen

Answer 4

Plasma cells

Question 5

Primary phagocytic cell in acute inflammation
Granules contain myeloperoxidase and lysozyme
Most common type of white blood cell
Multi-lobed nucleus

Answer 5

Neutrophil

Question 6

Releases histamine during allergic response
Granules contain histamine and heparin
Expresses IgE receptors on the cell surface
Bi-lobed nucleus

Answer 6

Mast cell

Question 7

Present in tissues and are similar in function to basophils but derived from different cell lines
Releases histamine during allergic response
Granules contain histamine and heparin
Expresses IgE receptors on the cell surface

Answer 7

Esoinophil

Question 8

Defends against protozoan and helminthic infections
Bi-lobed nucleus

Answer 8

Basophil

Question 9

Diffferentiates into macrophages
Kidney shaped nucleus

Answer 9

Monocyte

Question 10

Involved in phagocytosis of cellular debris and pathogens
Acts as an antigen presenting cell
Major source of IL-1

Answer 10

Macrophage

Question 11

Induce apoptosis in virally infected and tumour cells

Answer 11

Natural killer Cell

Question 12

Acts as an antigen presenting cell

Answer 12

Dendritic cell