Cell cycle Flashcards

1
Q

‘resting’ phase
quiescent cells such as hepatocytes and more permanently resting cells such as neurons

A

G0

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2
Q

Gap 1
cells increase in size
determines length of cell cycle
under influence of p53

A

G1

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3
Q

What regulatory proteins are involved in G1 phase of the cell cycle

A

Cyclin D / CDK4
Cyclin D / CDK6
Cyclin E / CDK2
regulates transition from G1 to S phase

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4
Q

Synthesis of DNA, RNA and histone
centrosome duplication

A

S phase

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5
Q

What regulatory proteins are involved in S phase?

A

Cyclin A / CDK2

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6
Q

Gap 2, cells continue to increase in size

A

G2

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7
Q

Regulatory proteins involved in G2

A

Cyclin B / CDK1: regulates transition from G2 to M phase

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8
Q

Mitosis - cell division
the shortest phase of the cell cycle

A

M phase

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9
Q

Which phase of the cell cycle determines the length of the cycle?

A

G1

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