Congenital infections

Question 1

Name 3 major congenital infections

Answer 1

rubella
toxoplasmosis
cytomegalovirus

Question 2

What is the most common congenital infection in the UK?

Answer 2

Cytomegalovirus (CMV)

Question 3

Maternal CMV infection is usually asymptomatic. TRUE/FALSE?

Answer 3

TRUE

Question 4

Characteristic features:
Sensorineural deafness
Congenital cataracts
Congenital heart disease (e.g. patent ductus arteriosus)
Glaucoma

What infection is this?

Answer 4

Rubella

Other features include:
Growth retardation
Hepatosplenomegaly
Purpuric skin lesions
‘Salt and pepper’ chorioretinitis
Microphthalmia
Cerebral palsy

Question 5

Characteristic features:
Cerebral calcification
Chorioretinitis
Hydrocephalus

What infection is this?

Answer 5

Toxoplasmosis

Other features include:
Anaemia
Hepatosplenomegaly
Cerebral palsy

Question 6

Characteristic features:
Low birth weight
Purpuric skin lesions
Sensorineural deafness
Microcephaly

What infection is this?

Answer 6

CMV

other features include:
Visual impairment
Learning disability
Encephalitis/seizures
Pneumonitis
Hepatosplenomegaly
Anaemia
Jaundice
Cerebral palsy