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MRCP Clinical sciences > HLA associations > Flashcards

HLA associations Flashcards

1
Q

Chromosome responsible for encoding of HLA

A

Chromosome 6.

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2
Q

Give examples of Class I vs Class II antigens

A

HLA A, B and C are class I antigens
DP, DQ, DR are class II antigens

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3
Q

HLA-A3

A

haemochromatosis

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4
Q

HLA-B51

A

Behcet’s disease

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5
Q

HLA-B27

A

ankylosing spondylitis
reactive arthritis
acute anterior uveitis
psoriatic arthritis

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6
Q

HLA-DQ2/DQ8

A

Coeliac

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7
Q

HLA-DR2

A

narcolepsy
Goodpasture’s

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8
Q

HLA-DR3

A

dermatitis herpetiformis
Sjogren’s syndrome
primary biliary cirrhosis

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9
Q

HLA-DR4

A

type 1 diabetes mellitus
rheumatoid arthritis

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10
Q
A
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MRCP Clinical sciences (114 decks)

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