Collagen Flashcards

1
Q

Collagen I is important for the formation of which structures

A

Bone, skin, tendon

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2
Q

Collagen II is important for the formation of which structures

A

Hyaline cartilage, vitreous humour

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3
Q

Collagen III is important for the formation of which structures

A

Reticular fibre, granulation tissue

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4
Q

Collagen IV is important for the formation of which structures

A

Basal lamina, lens, basement membrane

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5
Q

Collagen V is important for the formation of which structures

A

Most interstitial tissue, placental tissue

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6
Q

In which condition is there a defect in Collagen I

A

Osteogenesis imperfecta

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6
Q

In which condition is there a defect in Collagen III

A

Vascular Ehlers Danlos

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7
Q

In which conditions is there a defect in Collagen IV

A

Goodpastures, Alports

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8
Q

In which condition is there a defect in Collagen V

A

Classical Ehlers Danlos

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9
Q

Describe the structure of collagen

A

3 polypeptide strands that are woven into a helix
combination of glycine with either proline or hydroxyproline plus another amino acid

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10
Q

What makes collagen?

A

Fibroblasts

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11
Q
A
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