Collagen Flashcards
Collagen I is important for the formation of which structures
Bone, skin, tendon
Collagen II is important for the formation of which structures
Hyaline cartilage, vitreous humour
Collagen III is important for the formation of which structures
Reticular fibre, granulation tissue
Collagen IV is important for the formation of which structures
Basal lamina, lens, basement membrane
Collagen V is important for the formation of which structures
Most interstitial tissue, placental tissue
In which condition is there a defect in Collagen I
Osteogenesis imperfecta
In which condition is there a defect in Collagen III
Vascular Ehlers Danlos
In which conditions is there a defect in Collagen IV
Goodpastures, Alports
In which condition is there a defect in Collagen V
Classical Ehlers Danlos
Describe the structure of collagen
3 polypeptide strands that are woven into a helix
combination of glycine with either proline or hydroxyproline plus another amino acid
What makes collagen?
Fibroblasts