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Manajemen > Obat Off Label > Flashcards

Obat Off Label Flashcards

Obat off-label adalah penggunaan obat di luar indikasi yang tertera dalam label dan belum disetujui BPOM. Informasi obat off-label sangat terbatas, umumnya tidak dijumpai dalam buku, brosur atau jurnal ilmiah kedokteran maupun farmasi. Obat off-label digunakan dengan dosis, indikasi, usia, cara pemberian, dan kontraindikasi yang berbeda dari obat on-label

1
Q

Amitriptilin

A

on label : antidepresi
off label : analgesik neuropatik

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2
Q

Asetilsistein

A

on label : mukolitik
off label : preventif CIN (contrast Induced Nephropaty)

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3
Q

Aspirin

A

on label : antinyeri
off label : antiplatelet

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4
Q

Bromocriptine

A

on label : parkinson, DM 2 dan akromegali
off label : tingginya hormon prolaktin yang menyebabkan amenorrhea, galaktorea dan prolaktinoma

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5
Q

Botulinum Toksin tipe A

A

on label : terapi strasbismus dan spasme hemifacial dan Blefarospasme
off label : kosmetik mata

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6
Q

Baclofen

A

on label: antispasmodik
off label: meredakan cegukan (hiccups)

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7
Q

Carbamazepin

A

on label: antiepilepsi
off label: mood stabilizer

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8
Q

Cyproheptadine

A

on label: antihistamin, antialergi
off label: penambah nafsu makan

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9
Q

carvedilol

A

on label: antihipertensi
off label: profilaksis pendarahan varises

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10
Q

Celecoxib

A

on label: NSAID COX 2
off label: profilaksis kanker kolorektal dan kanker payudara

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11
Q

Domperidone

A

on label: antimuntah - antimual
off label: meningkatkan hormon prolaktin -> pelancar ASI

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12
Q

Etinil estradiol

A

on label: kontrasepsi
off label: acne vulgaris tingkat moderate

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13
Q

Florourasil

A

on label : (injeksi) antikanker
off label: (topikal) karsinoma sel basal

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14
Q

Gabapentin

A

on label: antikejang dan neuralgia (nyeri saraf) post herpes
off label: gangguan bipolar, tremor/gemetar, profilaksis migrain, nyeri neuropatik

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15
Q

Ketotifen

A

on label: antialergi
off label: meningkatkan nafsu makan

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16
Q

Laktulosa

A

on label: konstipasi
off label: ensafalopati hati dan sirosis hati

17
Q

Lamotrigin

A

on label: antikonvulsan epilepsi
off label: nyeri neuropati

18
Q

Levamisol

A

on label: antelmintika
off label: immunomodulator

19
Q

Mebendazol

A

on label: antelmintika
off label: immunomodulator

20
Q

metformin

A

on label: oral antidiabetik
off label: PCOS, memperbaiki siklus haid

21
Q

Metoklorpamid

A

on label: antimuntah dan antimual
off label: pelancar ASI, mengatasi cegukan

22
Q

Misoprostol

A

on label: prostaglandin analog sebagai sitoprotektif pada ulkus peptikum
off label: induksi persalinan, namun kontraindikasi pada ibu hamil

23
Q

Minoxidil

A

on label: vasodilator
off label: kebotakan (alopecia)

24
Q

midazolam

A

on label: (injeksi) anestesi lokal
off label: (sirup) premedikasi operasi pada anak

25
Q

N-asetilsistein

A

on label: mukolitik
off label: profilaksis efek samping radiokontras dan terapi kulit

26
Q

Nifedipin

A

on label: antihipertensi
off label: tokolisis (menghambat kontraksi uterus)

27
Q

Olanzapine

A

on label: antipsikotik
off label: mual dan muntah pada post kemoterapi

28
Q

Propanolol

A

on label: antihipertensi
off label: anxiety disorder, profilaksis pendarahan varises

29
Q

Probiotik

A

on label: suplemen pencernaan
off label: penyembuhan luka (luka bakar, luka operasi, luka mjkosa ,ulut dan luka diabetes)

30
Q

Refocoxib

A

on label: NSAID COX 2
off label: profilaksis kanker kolorektal dan kanker payudara

31
Q

Sildenafil

A

on label: gangguan disfungsi ereksi
off label: hipertensi pulmonar pada anak < 18 tahun dan neonatus

32
Q

sertralin

A

on label: antidepresan
off label : mengatasi ejakulasi dini pada pria

33
Q

Spironolakton

A

on label: hipertensi, udem, gagal jantung
off label: acne vulgaris moderate

34
Q

Salbutamol

A

on label: asma
off label: hiperkalemia dan hiperkalemia pada gagal ginjal

35
Q

semaglutide

A

on label: DM 2
off label: menurunkan berat badan

36
Q

Tamsulosin

A

on label: BPH pada pria
off label: batu ginjal pada perempuan

37
Q

Tramadol

A

on label : analgesik
off label: ejakulasi dini

Manajemen (24 decks)

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