Non0-neoplastic dz of female reproductive tract Flashcards

1
Q

Trichomonas structure

A

large flagellated protozoa

REMEMBER, IT IS AN STD

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2
Q

What are the symptoms of trichomonas infection

A

Yellow vaginal discharge, dyspaerunia (painful intercourse), dysuria (painful urination)

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3
Q

What will teh cervix look like during a trichomonas infection?

A

Inflamed like a strawberry

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4
Q

Predisposing factors to Candida infection?

A

Diabetes Mellitus, Pregnancy, Oral contraceptives

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5
Q

Presentation of candida infection?

A

Cottage cheese appearance of discharge, discomfort, itching

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6
Q

If an HSV II infection reactivates in pregnancy, the newborn may acquire fatal infection during passage through the birth canal

A

Active herpetic lesions at the time of delivery necessitate a C-section.

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7
Q

Characteristic appearance of HSC infected cells in pap smear?

A

cytomegaly, multi-nucleation, intra-nuclear inclusions

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8
Q

Pelvic Inflammatory Disease causes

A
  • Gonococcus, Chlamydia, mycoplasma, enteric bacteria, strep and staph.

GMC, E, Staph Strep

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9
Q

Presentation of PID

A

lower abdominal pain, adnexal tenderness, prominent discomfort when the cervix is manipulated (chandelier sign)

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10
Q

Complications of PID?

A

ruptures of tubo-ovarian abscess, peritonitis, sepsis, infertility, bowel obstruction

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11
Q

Most common and most severe infection in women?

A

Gonorrhea

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12
Q

Structure of Neisseria Gonorrhoeae?

A

gram negative diplococcus

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13
Q

How does gonorrheal PID come about?

A

Spreads upward.

  • Ascends from periuthral glands and perivaginal glands through the cervix and the endometrial cavity where they cause acute cervicitis and endometritis.
  • Infection spreads on the mucosal surface of the fallopian tubes to the ovaries and pelvic organs
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14
Q

Most common site of ectopic pregnancy

A

fallopian tubes (95%)

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15
Q

Ectopic pregnancy presentation

A

sudden abdominal pain, shock like presentation about 6-12 weeks following a previous menstrual period.

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16
Q

Physiology of menstrual cycle slide

A

know it

17
Q

During the proliferative phase, how would you characterize the endometrium?

A

Straight glands with psuedo-stratified epithelium.
No mucin production
Stroma is composed of spindle cells with scant cytoplasm, high mitotic rate

18
Q

Labia major covered by

A

skin

19
Q

Labia minor

A

non-keratinizing squamous epithelium

20
Q

Endocervical canal lined by?

A

glandular epithelium

21
Q

Upper 2/3 of the endometrum is called

A

zona functionalis

22
Q

Lower 1/3 is the basal layer

A

of the endometrium

23
Q

What does the trichomonas vaginalis organism look like?

A

Its a protozoa, looks a lot like a neutrophil swimming around

24
Q

Gross appearance of PID

A

adnexa show mall like conglomerates replacing the tubes and ovaries. Inflamed tube and ovaries surrounded by fibrous tissue
The masses are composed of inflammatory exudate, necrotic debris, and fibrous tissue.
May rupture causing peritonitis/ sepsis. May also turn into a sac containing clear fluid

25
Q

Endometrial hyperplasia

A

Prolonged, abnormally high estrogen stimulation without progesterone effect

26
Q

Conditions that cause endometrial hyperplasia?

A

Stein-leventhal syndrome, perimenopause, estrogen tumors, obesity

27
Q

What is the normal gland to stroma ratio

A

50:50

28
Q

What is the gland to stroma ratio in endometrial hyperplasia?

A

DOMINATING GLANDS over stroma

29
Q

What is a chandelier sign?

A

Discomfort when the cervix is manipulated…suggests PID

30
Q

Primary infxn that causes PID?

A

Post-partum endometriosis, Intrauterine device, curretage

31
Q

More common cause of PID is the introduction of organisms through sex

A

ok

32
Q

What causes the infertility in PID patients

A

stricture of the fallopian tubes

33
Q

Two most common causes of PID

A

chlamydia and gonorrhaea

34
Q

What does the post-menopausal endometrium look like?

A
  • inactive or simple cystic glands
  • No evidence of proliferation or secretion
  • ## Dense inactive stroma
35
Q

KNOW…In hyperplasia, there is no secretion!!! If you see mucin, it is not hyperplasia

A

ok

36
Q

WHen looking for hyperplasia, look for glands with no stroma between them and no secretion

A

ok