Gynecologic path- Nichols Flashcards
Uterine cervical squamous epithelium (normal) description
Single layer of basal cells
As the cells get higher, they get flatter
Cytoplasm has tons of glycogen in it
Dysplasia causes cells in the epithelial layer (top) to look more like?
Basal cells
Triple negative breast cancer is twice as common in what race
blacks
Triple negative BC is more common in what age group
younger, premenopause
Triple neg bc is more common in
blacks, younger, obese, children at a younger age
70% of pts with a …. mutation get triple neg BC
BRCA
Triple negative is bad
highly malignant, higher stage, higher grade at presentation
Triple neg most commonly mets to where?
brain, lung, liver, distant nodes, less commonly to bone