Neutropenic sepsis

Question 1

What is the criteria for neutropenic sepsis?

Answer 1

Fever >38*C or infective symptoms
AND
Neutrophils <0.5 or <=1 if cytotoxic chemo within previous 21 days

Question 2

What is a standard risk patient with neutropaenic sepsis?

Answer 2

NEWS <=6

Question 3

What is a high risk patient with neutropaenic sepsis?

Answer 3

Septic shock OR NEWS>=7

Question 4

What are the empirical antibiotics for standard risk neutropaenic sepsis?

Answer 4

Piperacillin-Tazobactam

Question 5

What are the empirical antibiotics for high risk neutropaenic sepsis?

Answer 5

Piperacillin-Tazobactam AND gentamicin

Question 6

What do you replace piperacillin-tazobactam with if there is a penicillin allergy?

Answer 6

Teicoplanin and aztreonam

Question 7

What do you replace piperacillin-tazobactam with if there is angioedema or anaphylaxis?

Answer 7

Teicoplanin and ciprofloxacin

Question 8

Do you need to wait for FBC to come back before treating suspected neutropaenic sepsis?

Answer 8

NO