BNF Antibiotic Guidelines

Question 1

Exacerbations of chronic bronchitis

Answer 1

Amoxicillin
OR
Tetracycline
OR
Clarithromycin

Question 2

Uncomplicated CAP

Answer 2

Amoxicillin
Doxy or clarithromycin if allergic
Fluclox if staph suspected e.g. flu

Question 3

Atypical CAP

Answer 3

Clarithromycin

Question 4

Hospital acquired pneumonia

Answer 4

Within 5 days of admission: co-amoxiclav or cefuroxime
More than 5 days after admission: piperacillin with tazobactam OR a broad-spectrum cephalosporin (e.g. ceftazidime) OR a quinolone (e.g. ciprofloxacin)

Question 5

Lower UTI

Answer 5

Nitrofurantoin or trimethoprim
Second line amoxicillin or cephalosporin

Question 6

Pyelonephritis

Answer 6

Broad spectrum cephalosporin or quinolone

Question 7

Acute prostatitis

Answer 7

Quinolone
OR
Trimethoprim

Question 8

Impetigo

Answer 8

Topical hydrogen peroxide
Oral flucloxacillin or erythromycin if widespread

Question 9

Cellulitis

Answer 9

Flucloxacillin
clarithromycin, erythromycin or doxycycline if penicillin-allergic

Question 10

Cellulitis near eye or nose

Answer 10

Co-amoxiclav (clarithromycin, + metronidazole if penicillin-allergic)

Question 11

Erysipelas

Answer 11

Flucloxacillin (clarithromycin, erythromycin or doxycycline if penicillin-allergic)

Question 12

Animal or human bite

Answer 12

Co-amoxiclav (doxycycline + metronidazole if penicillin-allergic)

Question 13

Mastitis during breast feeding

Answer 13

Flucloxacillin

Question 14

Throat infection

Answer 14

Phenoxymethylpenicillin (erythromycin alone if penicillin-allergic)

Question 15

Sinusitis

Answer 15

Phenoxymethylpenicillin

Question 16

Otitis media

Answer 16

Amoxicillin (erythromycin if penicillin-allergic)

Question 17

Otitis externa

Answer 17

Flucloxacillin (erythromycin if penicillin-allergic)

Question 18

Periapical or periodontal abscess

Answer 18

Amoxicillin

Question 19

Gonorrhoea

Answer 19

IM ceftriaxone

Question 20

Chlamydia

Answer 20

Doxycycline or azithromycin

Question 21

Pelvic inflammatory disease

Answer 21

Oral ofloxacin + oral metronidazole
OR
IM ceftriaxone + oral doxycycline + oral metronidazole

Question 22

BV

Answer 22

Oral or topical metronidazole or topical clindamycin

Question 23

C. diff

Answer 23

First episode: oral vancomycin
Second or subsequent episode of infection: oral fidaxomicin

Question 24

Campylobacter enteritis

Answer 24

Clarithromycin

Question 25

Salmonella (non-typhoid)

Answer 25

Ciprofloxacin

Question 26

Shigella

Answer 26

Ciprofloxacin