Endocarditis Causative Organisms and Treatment

Question 1

Acute native valve endocarditis organism

Answer 1

Staph aureus

Question 2

Subacute native valve endocarditis organisms

Answer 2

Viridans strep
Enterococci

Question 3

Prosthetic valve endocarditis organisms

Answer 3

MRSA
Coagulase negative staph

Question 4

Native valve acute blood culture guidelines

Answer 4

2 sets of blood cultures
Start Abx within the hour

Question 5

Native valve subacute blood culture guidelines

Answer 5

3 sets blood cultures 6 hours apart if patient stable

Question 6

Native valve indolent empirical antibiotics

Answer 6

Amoxicillin IV
Consider adding gentamicin

Question 7

Native valve acute empirical antibiotics

Answer 7

Flucloxacillin IV

Question 8

Suspected MRSA native valve acute empirical antibiotics

Answer 8

Vancomycin IV
Gentamicin IV
Rifampicin (3-5 days later) PO

Question 9

Prosthetic valve endocarditis empirical antibiotics

Answer 9

Vancomycin IV
Gentamicin IV
Rifampicin (3-5 days later) PO

Question 10

Native valve acute with risk factors for resistant pathogen empirical antibiotics

Answer 10

Vancomycin
+
Meropenem (if
ESBL or suspicion of
Pseudomonas )