Neurotransmitters Flashcards

1
Q

What does Serotonin regulate?

A

Mood, anxiety and sleep

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2
Q

What are the serotonin receptor types?

A

19 subtypes - ALL GPCR except 1

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3
Q

Are the serotonin receptors inhibitory or excitatory?

A

Both! - Depends on the receptor

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4
Q

What does Acetylcholine regulate?

A

Learning and memory, attention, and muscle movement

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5
Q

What are the types of Acetylcholine receptors?

A

Nicotinic and Muscarinic

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6
Q

What are the characteristics of the nicotinic ACh receptors?

A

Ionotropic and EXCITATORY

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7
Q

What are ALL the dopamine receptors?

A

D1-D5

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8
Q

What are the characteristics of the muscarinic ACh receptors?

A

GPCR’s - Inhibitory and Excitatory

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9
Q

Where do the D1 and D5 receptors function?

A

Ventral Tegmental Area

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10
Q

What do the D1 and D5 receptors regulate?

A

Reward, emotion, reinforcement, and addiction

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11
Q

Are D1 and D5 receptors excitatory or inhibitory?

A

Both! - Stimulates cAMP production

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12
Q

Where does D2-D4 receptors function?

A

Substantia Nigra

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13
Q

What do the D2-D4 receptors regulate?

A

Motor Control

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14
Q

What happens if the D2-D4 receptors die?

A

Development of Parkinson’s

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15
Q

Are D2-D4 receptor inhibitory or excitatory?

A

Inhibitory - Inhibits cAMP production

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16
Q

What do Norepinephrine receptors regulate?

A

Emotional arousal, mood, sexual behavior, and learning/memory

17
Q

What are the 4 NE receptor subtypes?

A

a1, a2, b1, and b2

18
Q

What are the characteristics of a1 NE receptors?

A

Excitatory - Activates Phosphorylase

19
Q

What are the characteristics of a a2 NE receptor?

A

Inhibitory - Inhibits cAMP production / often an auto receptor

20
Q

What are the characteristics of b1 and b2 NE receptors?

A

Excitatory - Stimulates cAMP production

21
Q

What are the GABA receptors?

A

GABA A and GABA B

22
Q

What are the characteristics of GABA A receptors?

A

Ionotropic - Chloride channels - INHIBITORY

23
Q

What are the characteristics of GABA B receptors?

A

Metabotropic - INHIBITORY

24
Q

GABA receptors are always…

A

Inhibitory

25
Q

What type of neuron is a GABA neurotransmitter?

A

Interneuron except for in the striatum (primary projection neurons)

26
Q

What type of neuron is a Glutamate neurotransmitter?

A

Primary projection neuron of most forebrain structures

27
Q

What are the Glutamate receptors?

A

iGluRs and MGluRs

28
Q

What are the characteristics of iGluRs?

A

Ionotropic - AMPA, Kainate, NMDA (EXCITATORY)

29
Q

What are the characteristics of MGluRs?

A

Metabotropic - EXCITATORY

30
Q

Glutamate receptors are always…

A

EXCITATORY