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A-CNS physio > Neurotransmitters > Flashcards

Neurotransmitters Flashcards

1
Q

بسم الله الرحمن الرحيم وبه نستعين
اللهم ادخلني مدخل صدق واخرجني مخرج صدق واجعل لي من لدنك سلطانا نصيرا
___________________________
NeuroTranmitters ?

A

Endogenous substance communicating nuerons with each other and effectors

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2
Q

Classify Nts at
size and speed

A

Small rapidly acting:
Ahmed CAN
Ach _ Catechoamines -aminoacids -Nitric Oxide
Large slowly acting:
2P+H
Peptides + pituitary peptides
Hypothalamic releasing Hormones

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3
Q

NTs Works in ?

A

Local
Nearby neurons
Horomnes in blood

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4
Q

What is neostigmine ?

A

Short acting cholinestrases used in myathenia gravis

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5
Q

Therapy of Myathenia gravis

A

Neostigmine+Cortisol

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6
Q

Dopamine site and effect and receptor nembers ?

A

Basal ganlgia +limbic system
Inhibitory effect
5 receptors Ds

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7
Q

NE found in ?

A

Brainstem Pons+Medulla oblongata

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8
Q

Ach released from ?
Effect?
Receptors ?

A

Motor Cortex + Thalamus
Eciatatory
Muscarininc + Nicotinic receptors

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9
Q

Ach responsible for?

A

arousal as histamine + Learning

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10
Q

Decreasd Ach in ?

A

Alzhemir
Myathenia Gravis

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11
Q

Dopamine imbalance cause ?

A

decreasd= parkinsosinsm
Increased=Schizophrenia

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12
Q

NE IS EXCITATORY OR INHIBITORY?

A

Excitatory + inhibitory
Excita Alpha 1
Inhibits B2

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13
Q

أيه اهمية النور ادرينالين في حياتك ؟

A

BMAroF
BP Regulation
Mood as serotonin
Arousal as histamine +Ach
Feeding desire

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14
Q

Decreased NE casuse?

A

AdhD
ADHD
Depression
Hypotension

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15
Q

NTs casuing arousal ?

A

NE
Histamine
Ach

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16
Q

طيب الادرينالين محفز ولا مثبط ؟

A

محفز ومثبط
محفز الفا 1
مثبط بيتا 2

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17
Q

Compare between E and NorE IN SITE

A

NE brainstem Pons +Medulla
E brainstem Reticular Formation

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18
Q

Pheochrmomcytoma effects?

A

Attacks ! of
Hypertension
Hyper glycemina
why attacks ?
due to the propttion of E is pulsatile ! increasing then decrasing

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19
Q

Compre between site of Serotonin and NE

A

Each from brainstem but?
Serotonin: Midbrain+pons
NE:pONS+Medulla
so thay have Pons in common

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20
Q

ليه الكوكاين بيعمل ادمان ؟

A

blocking reuptake of E+NE+Dopamine
casuing Euphoria

21
Q

Serotonin function

A

NT+
MOOD releving pain
appetite + temperatue regulation
Melatonin for sleep
Smooth muscle contraction
Git muscel contraction
Feeding as NE

22
Q

Mention 2NT for feeding ?

A

Serotoinin
Ne

23
Q

NT for sleeping

A

Serotonin and Melatonin

24
Q

mention clincal application for serotoonin

A

LSD incrasing serotinin and hallucination

25
Q

Histamine appear in ?

A

Hypothalmus + Pituitary

26
Q

Mention types of histamine receptors

A

H1 = AROUSAL
H2= HCL
H3=SELF INHIBIITON
H4=Bone marrow for WBCs synthesis Regulation

27
Q

MAOI double edged weapon

A

Increasing dopamine releiving parkinsonsm
increasing NE +E F casuing HTN

28
Q

pRinciple Inhibitory NT ?

29
Q

Functions of GABA 1

A

presynaptic inhibtion

30
Q

Benzodiazpine functions

A

incrasing ability of GABA to activate its receptrors so works as
3antis+s
Anxiolytics
antispamodic
antiConvulsants
Sedative+hypnotics

31
Q

Alzhemir imbalnce of Neurotranmsitter occure show !

A

Decreased Ach
Increased Glutamte

32
Q

Compare glycine and GABA

A

glycine post synaptic inhibtion
GABA presynaptic inhibtion

33
Q

Compare between site of glycine and NE

A

Glycine Meudulla + Spinal cord
NE: pONS + MEDULLA
they have Medulla in common

34
Q

glycine blocking?

A

Strychnine

35
Q

Princpale inhibotry
princeple excitatory

A

1- GABA
2-GLUTAMTE

36
Q

Glutamte is called Excitotoxin why?

A

As its level if rised severly casuing Sever Excitation and Neurotoxicity

37
Q

Mention 3 cases in which glutamte increases

A

Alzhemir
Stroke
Parkinsonism
ASPPPPPP

38
Q

The Only NT secreted By Demand?

A

Nitric Oxide

39
Q

NO found in and functions?

A

Limbic system as dopamine
Memory+emotions

40
Q

Substance p

A

Pain excitor
in brainstem + spinal cord
it is slowly acting

41
Q

hYpothalmic Relasing Hormones Mention

A

CTPGG
Corticotrohins realsing hormones for ACTH
tHYROtrophin relasing hormone TSH
pROLactin releasing hormones for Prolactin
Gonadotropins releasing hormones for FSH -LH
Growh hormone releasingg Hormone

42
Q

Strong inhibtion of pain ?

43
Q

Neurohormones

A

hypothalamic relasing hormones

44
Q

Ach appear in ?

A

Motor cortex
THALAMJS 2 HIGHRST CONC
Basal ganglia
Preganglionic autonimc
post ganglionic para
post ganglionic symp for ?
1-sweat glands + blood vessels

45
Q

Adenosins atp NO

A

aRE NEUROMODULATOR MODULATING THE ACTION OF NEURONS FOR LONG TIME

46
Q

GABA WORK

A

OPEN CL- Chs casuing hyperpolarization

47
Q

receptor of glutamate

A

NMDA AMPA KINATE

48
Q

Opiod peptides ?

A

Morphine like acions

49
Q

تم بحمد الله

A-CNS physio (29 decks)

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