Neurology Flashcards

1
Q

Tetanus/aetiology, pathogenesis/dog?

o Clostridium tetani infection -> encephalitis -> spastic paralysis
o Anaerobe wound + Clostridium tetani infection -> tetanospasmin-formation -> GABA and glicin inhibition
o Enteral absorption of tetanospasmin -> neuromuscular paralytic effect
o Enteral absorption of tetanospasmin -> GABA and glicin activation

A

o Anaerobe wound + Clostridium tetani infection -> tetanospasmin-formation -> GABA and glicin inhibition

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2
Q

Difference in rabies and Aujeszky´s disease symptoms in dog and cat?

o Paresthesia is common in Aujeszky´s disease, offensive behaviour is common in rabies
o Strabismus and ascending limb paralysis are common in Aujeszky´s disease, paresthesia is common in rabies
o Swallowing disorder does not occur in Aujeszky´s disease only in rabies. The aquifer is typical of Aujeszky´s disease
o Rabies in cats does not occur, only Aujeszky´s disease

A

o Paresthesia is common in Aujeszky´s disease, offensive behaviour is common in rabies

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3
Q

Rabies vs. Aujeszky’s disease/differences in symptoms/dog and cat?

o Anisocoria and paresthesia are common in Aujeszky’s disease, attacking behaviour is common in rabies
o Strabismus and ascending limb paralysis are common in Aujeszky’s diseases, paresthesia is common in rabies
o Dysphagia do not occur in Aujeszky’s diseases, only in rabies, Lung oedema is characteristic in Aujesky’s disease
o Rabies does not occur in cats, only Aujeszky occurs in cats

A

o Anisocoria and paresthesia are common in Aujeszky’s disease, attacking behaviour is common in rabies

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4
Q

Which medicine can be used to relieve seizures?

o Diazepam
o Propofol
o Both
o None

A

o Both

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5
Q

What is the most likely cause of a seizure in a young adult dog?

o Congenital heart disease
o Primary epilepsy
o Portosystemic shunt
o Brain tumor

A

o Primary epilepsy

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6
Q

Lurking of rabies (if they mean incubation)

o It is usually 2-3months, but can be shorter or longer, depending on the location of the infection
o Symptoms of OA rabies develop within 3-7 days after infection
o OA rabies incubation period is very short, symptoms occur within 1-2 days after infection
o Usually 1-2 weeks, but can be shorter if the milling has hit the first limbs

A

o It is usually 2-3months, but can be shorter or longer, depending on the location of the infection

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7
Q

Which statement is true for congenital hydrocephalus?

o A hydrocephalus is common in flatal (less than 1 year) individuals of large dogs
o Ventriculoperitoneal shunt implantation in dogs may be used for palliative symptomatic treatment
o Glucocorticoid and diuretic therapy is contraindicated in individuals with high intracranial pressure
o Hydrocephalus is very rare in flatal (less than 1 year) individuals of small dogs

A

o Ventriculoperitoneal shunt implantation in dogs may be used for palliative symptomatic treatment

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8
Q

A 3-year-old Labrador has experienced 2 seizures in the last 2 months. Other than that, nothing did not detect any abnormality in his dog. What is the most likely diagnosis?

o Idiopathic epilepsy
o Structural epilepsy, presumably due to a congenital brain disorder.
o Reactive epileptic seizures due to compulsive eating in labradors.
o Portosystemic shunt (given the age of animal)

A

o Idiopathic epilepsy

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9
Q

Which spinal disease is painful?

o Discopathy
o Fibrocartilago embolism
o Degenerative myelopathy
o Wobbler syndrome

A

o Discopathy

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10
Q

Where is the most characteristic localization of vertebral body tumors?

o In the middle of the third vertebral bodies
o In end plates
o Multifidarius processes
o Articular process

A

o In the middle of the third vertebral bodies

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11
Q

The modified Glasgow coma scale assesses brain damage based on;

o Pupil size, motor activity, state on consciousness
o Pupillaray reaction, motor activity, brainstem reflexes
o Brainstem flexes, motor activity, state of consciousness
o Pupil size, brainstem reflexes, state of consciousness

A

o Brainstem flexes, motor activity, state of consciousness

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12
Q

How can we diagnose deep pain?

o To tighten/pinch patient’s finger
o The patient squeezed his finger, stretching out the limb on the opposite side
o After pinching/squeezing a patient’s finger, he pulls out, turns his head, vocalizes, tries to bite.
o After painful stimulation, the M.cutaneus trunci contracts

A

o After pinching/squeezing a patient’s finger, he pulls out, turns his head, vocalizes, tries to bite.

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13
Q

What means cervical malformation & malarticulation?

o Wobbler syndrome
o Cauda equina syndrome
o Perthes disease
o Sever’s disease

A

o Wobbler syndrome

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14
Q

What situation does taken CSF sample help diagnosis

A

o Meningitis

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15
Q

Why are cats sensitive to pyrethrins?

A

o Hepatic glucuronidase activity is low → decr. metabolism → toxicosis (seizures/tremors)

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16
Q

Which instrumental additional test is best for diagnosing fibrocartilago embolism

o X-ray
o CT
o MRI
o Liqour cytology

A

o MRI

17
Q

Which cannot be a symptom of transverse myelopathy

o	partiality 
o	lameness
o	Ataxia
o	Hyperreflexia 
o	Proprioceptive disorder
A

o Ataxia

18
Q

Which is not true for degenerative myelopathy?

o It is a nutritional problem
o Slowly progressive axonal degeneration and demyelinisation
o Most frequent is older german shepherd dogs
o No curative treatment

A

o It is a nutritional problem

19
Q

Cervicalstenotic myelopathy/ diagnostics

o Measuring vitamin E and selenium
o CSF sampling
o Cervical CT examination
o Myelography

A

o Myelography

20
Q

What disease is this dog suffering from ? (terrier on a table, lateral recumbency)

o Aujeszky disease
o Botulism
o Meningioencephalitis
o Tetanus

A

o Botulism

21
Q

Prevention of epilepticseizures/medication/dog?

o Diazepam, dexamethasone, phenytoin
o Phenobarbital, potassium-bromide
o Nitrazepam, progabide, phenobarbital

A

o Phenobarbital, potassium-bromide

22
Q

Rabies/incubation period?

o Usually 2-4 weeks, but can be shorter or longer, depends on which body part was infected
o Symptoms start 3-10 days after infection
o Incubation period is very short, symptoms start 1-2 days after infection
o Usually 2-4 months, but can be longer if the hind limbs of the patient had been bitten

A

o Usually 2-4 months, but can be longer if the hind limbs of the patient had been bitten

23
Q

Neurophysiologic background of botulism?

o Paralysis of the striated muscles due to inhibited released of GABA at the presynaptic motor nerve endings
o Paralysis of the striated muscles due to inhibited release of acetylcholine at the presynaptic motor nerve endings
o General muscular paralysis due to inhibited release of acetylcholine at the presynaptic motor nerve endings
o Paralysis of striated muscles due to inhibited release of GABA at postsynaptic motor n. endings

A

o Paralysis of the striated muscles due to inhibited release of acetylcholine at the presynaptic motor nerve endings

24
Q

D-vitamin toxicity/Which of the below statements is false?

o In dogs it is more frequent, because cats have higher tolerance to vitamin D
o Chronic vit D-toxicity causes transient hypercalcaemia, soft tissue calcification, mineralisation of long bones
o Acute D-vit toxicity causes vomiting, hypercalcaemia, hypoglycaemia, ataxia, epileptiform seizures
o Useful in D-vit toxicosis, treatment: charcoal, IV fluid therapy, sucralphate, prednisolone, furosemide

A

o Acute D-vit toxicity causes vomiting, hypercalcaemia, hypoglycaemia, ataxia, epileptiform seizures

25
Q

Rabies vs. Aujeszky’s disease/course/dog and cat?

o Overlapping between the course of the two diseases is possible
o The course of Aujeszky’s disease is always longer in comparison to rabies
o The course of these two diseases is usually longer than one week
o The course of these two diseases is usually shorter than one day

A

o Overlapping between the course of the two diseases is possible

26
Q

Idiopathic headshaking/cause

o Bad habit
o Trigeminal neuralgia
o Tooth problem
o Sensitivity to flies

A

o Trigeminal neuralgia

27
Q

Tetanus/Dog/Which statement is not true?

o Tetanus can be diagnosed simply based on the history and clinical signs
o Saw-horses posture is characteristic for the disease
o Diazepam can be administered as sedative agent both intravenously and rectally
o Partial tetanus is more common than the generalised form

A

o Partial tetanus is more common than the generalised form

28
Q

On this schematic illustration the lesion (red) is at the C1-C5 segments of the spinal cord. Which statements are correctly indicated by the abbreviations?

o UMN to the front limbs, UMN to the rear limbs
o LMN to the front limbs, UMN to the rear limbs
o UMN to the front limbs, LMN to the rear limbs
o LMN to the front limbs, LMN to the rear limbs

A

o UMN to the front limbs, UMN to the rear limbs

29
Q

Lissencephaly (lyssencephalon)/Definition?

o Complication of hydrocephalus
o Congenital under-development (lack of development) of the sulci and gyri of the cortex
o One type of metabolic storage disorders of the brain
o Histopathological alteration of the brain as a sequel of rabies (lyssa)

A

o Congenital under-development (lack of development) of the sulci and gyri of the cortex

30
Q

For what disease is this posture characteristic? (st. bernard puppy, legs straight out on both sides)

o Encephalomyelitis caused by canine
o Tetanus
o Botulism
o Hydrocephalus with brain stem abscess

A

o Hydrocephalus with brain stem abscess

31
Q

What kind of disease can be seen in the picture?

o Cervical vertebral instability
o Vertebral fractur
o Cervical static stenosis
o Osteoporosis

A

o Cervical vertebral instability

32
Q

• What statement is correct regarding the imaging of spinal cord compression (SCC)

o Disc calcification indicated SCC
o A survey radiograph is generally enough to diagnose SCC
o SCC can be caused exclusively by the intervertebral disc
o Myelography is useful tool in the diagnostics of SCC

A

o Myelography is useful tool in the diagnostics of SCC

33
Q

Which statement is correct

o Wobbler-syndrome affects small breeds
o The site of disc protrusion can be exactly determined in the survey radiograph
o The basic types of compressive processes found with myelography: extradural, intradural, extramedullary
o Positioning of cervical spine generally needs sedation or anesthesia

A

o Positioning of cervical spine generally needs sedation or anesthesia

34
Q

Which of the following breeds is mostly predisposed to Wobbler syndrome

o Dobermann
o German shepherd
o Dachshound
o Labrador retriever

A

o Dobermann