Liver Flashcards
Which statement is NOT true for lymphocytic cholangitis in cat?
o The most common form of the cholangitis in cat
o The cause and pathogenesis are not really clear. Suspected immune-mediated procedure
o The Persian cat is predisposed
o The result of bile culture obtained by cholecystocentesis adherens invasive E coli (AIEC)
The result of bile culture obtained by cholecystocentesis adherens invasive E coli (AIEC)
Which statement if NOT true?
o Antiepileptic therapy could cause elevated ALP, ALT and GGT level in dog
o The potentiated sulphonamide therapy can cause a destructive cholangitis in dog
o The glucocorticoid therapy always lead an irreversible necrosis in the liver
o The antidote of the acetaminophen toxicosis is the N-acetylcystine
The glucocorticoid therapy always lead an irreversible necrosis in the liver
The upper limit of total bilirubin in the dog is o 10 mikromol/l o 40 mikromol/l o 10 mmol/l o 40 mmol/l
10 mikromol/l (umol)
Which statement is true?
o The acute liver failure regardless of cause can be classified by activation of Stellate cells, fibrosis
o The blood level of the hepatocellular enzymes (ALT, AST) is elevated primarily in case of necrosis, inflammation, increased permeability of the hepatocyte membrane
o The bilirubinuria is always pathologic in dog, associated always with bilirubinuria
o In cholestasis mostly the ALT and AST are elevated
The blood level of the hepatocellular enzymes (ALT, AST) is elevated primarily in case of necrosis, inflammation, increased permeability of the hepatocyte membrane
Hepatitis caused by viruses/dog and cat
o Canine distemper (CAV-1), Calicivirus, FIV
o Rubarth disease (CAV-1), panleukopenia, FeLV
o Rubarth disease (CAV-1), herpesvirus caused hepatitis, FIP
o FIP, Calicivirus, Mycoplasmosis
Rubarth disease (CAV-1), herpesvirus caused hepatitis, FIP
Which statement is not typical for cat?
o The common bile duct joins the major pancreatic duct before entering the duodenum
o The acute neutrophil cholangitis is the consequence of ascending bacterial infection
o The hepatic encephalopathy is a common consequence of the feline hepatic lipidosis due to the arginine deficiency
o The portal hypertension, ascites and PU/PD are common signs in hepatopathies of the cat
The portal hypertension, ascites and PU/PD are common signs in hepatopathies of the cat
What is responsible for the signs suffering from hepatopathy?
o Ammonia
o Scatole
o Intracranial haemorrhage
o Hypoglycaemia
Ammonia
Which disease is accompanied by ascites in cat?
o Hepatic lipidosis
o Lymphocytic cholangitis
o Neutrophilic cholangitis
o Congenital portosystemic shunt
Lymphocytic cholangitis
Which statement is FALSE? feline hepatic lipidosis
o It is increased by intrahepatic cholestasis
o Bile acid, bilirubin, ALT and ALP were elevated, while GGT was disproportionaly low
o Clinical symptoms: obese cat losing weight, jaundice, salivation, coagulopathy and hepatomegaly.
o Increased lipoprotein synthesis due to starvation, resulting in decreased triglyceride levels in liver
Increased lipoprotein synthesis due to starvation, resulting in decreased triglyceride levels in liver
What sickness causes portal hypertension?
Connected to hepatic arterio-venosus fistula (AVF) (also hepatic venous outflow obstruction)
Which IS associated with portal hypertension?
o Hepatic microvascular hypoplasia
o Arterioportal/arterio-venosus fistula
o Congenital portosystemic shunt
o Hepatic lipidosis
Arterioportal/arterio-venosus fistula
Which statement is NOT true?
o The bilirubinuria is always pathologic in cats associated with hyperbilirubinaemia
o The ALP-isoenzymes in the cat: liver, bone, steroid induced isoenzymes
o The ALT and AST are hepatocellular enzymes
o The bile acid, ALP, GGT levels are elevated in cholestasis
o The ALP-isoenzymes in the cat: liver, bone, steroid induced isoenzymes
Which disease is associated with ascites in cats?
o Neutrophilic cholangitis
o Portosystemic shunt
o Lymphocytic cholangitis and biliary cirrhosis
o Hepatic lipidosis
Lymphocytic cholangitis and biliary cirrhosis
Which statement is NOT characteristic for the primer Cu accumulation?
o Progressive, life-long Cu accumulation
o Centrolobular zona
o Beddlington terrier, Labrador and Dalmatian have primer Cu accumulation
o The Cu accumulation is caused by cholestasis
The Cu accumulation is caused by cholestasis
Which statement is NOT characteristic for the seconder Cu accumulation?
o The liver damage is not proportional with the Cu level of the liver
o Periportal
o Dobermann, Labrador, and Dalmatian have seconder Cu accumulation
o The Cu accumulation is caused by cholestasis
Dobermann, Labrador, and Dalmatian have seconder Cu accumulation
Which statement is false EOGC (eosinophil granuloma complex)
o Eosinphilia is possible in the blood
o Allergy plays a role in pathogenesis
o Can only be diagnosed with RTG
o Cyclosporine is possible theraphy method
Can only be diagnosed with RTG
Which is the first-choice drug in the treatment of primary Copper storage disease?
o D-penicillamine
o Glucocorticoid
o Omeprazole
o Zn and cholagogue drugs
D-penicillamine
Characteristic of lymphangiectasia
Ascites, hydrothoravx, weight loss, emaciation
Lymphangiectasia/characteristics/dog, cat?
o Severe disorder of colon
o Leads to protein losing enteropathy in severe case
o Specific diagnosis established with measurement of serum concentration of folate & cobalamine
o High fat diet is suggested because of severe malnutrition
Leads to protein losing enteropathy in severe case
In what kind of disease is this breed predisposed? (Doberman picture)
o Familiary, chronic hepatitis
o Epulis
o Congenital aortic stenosis
o Tracheal hypoplasia
Familiary, chronic hepatitis
Which statement is NOT true for chronic hepatitis in dog?
o Periportal mononuclear cell infiltration, inflammation, periportal necrosis, fibrosis
o Centrolobular mononuclear cell infiltration, inflammation, centrolobular necrosis, fibrosis
o Chronic procedure, no improvement for 4-6 weeks
o The histopathology is independent from the cause
Centrolobular mononuclear cell infiltration, inflammation, centrolobular necrosis, fibrosis
Which is NOT a form of vena portae hypoplasia?
o Hepatic microvascular hypoplasia
o Arterioportal / arteriovenosus fistula
o Idiopathic noncirrhotic portale hypoplasie
o Hepatiportal fibrosis
Arterioportal / arteriovenosus fistula
Which statement is NOT true?
o In hepatic encephalopathy the blood level of ammonia is elevated
o The lactulose and diet with high biologic values protein are an important part of the treatment of the hepatic encephalopathy
o Precipitating factors in hepatic encephalopathy are the obstipation, alkalosis, hypokalaemia and GI bleeding
o In microvascular dysplasia the abnormal blood vessels can be detected by colour doppler ultrasound
In microvascular dysplasia the abnormal blood vessels can be detected by colour doppler ultrasound
What are the lesions on this picture?
o Fusobacteria induced hepatic necrosis
o Hepatocellular carcinoma
o Chronic fibrinous perihepatitis
o Signs of Ascaris larval migration
Signs of Ascaris larval migration
