neuro lec 5 Flashcards

1
Q

Diff bw arterial vs venous system?

A
  • Arterial: supplies oxygenated blood to brain, includes arteries, arterioles, capillaries.
  • Venous: removes deoxygenated blood from brain back to heart/lungs, includes venules, veins, sinuses.
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2
Q

Why do brain cells require constant oxygen and glucose?

A

Because brain does not store these things

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3
Q

Diff bw systolic vs diastolic pressure?

A
  • Systolic = away from heart
  • Diastolic = passive return of blood towards heart
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4
Q

What are the parts of the internal carotid system? (2)

A
  • Anterior cerebral arteries
  • Middle cerebral arteries
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5
Q

What are the parts of the vertebrobasilar system? (2)

A
  • cerebellar arteries (several)
  • Right and left vertebral arteries form the basilar artery at the level of the pons
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6
Q

What is the circle of Willis?

A
  • Where the basilar artery joins the internal carotid system at the base of the brain
  • Allows for collateral circulation (alternative routes in case of blockage)
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7
Q

Whats the connection bw vertebral arteries and posterior cerebral arteries?

A

Vertebral arteries go into the skull from the neck and join together into the basilar artery which then joins the circle of willis and turns into the posterior cerebral arteries

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8
Q

Whats the connection bw the internal carotid and the anterior/middle cerebral arteries?

A

Internal carotid go into the skull from the front of the neck and joins the circle of willis becoming the anterior/middle cerebral arteries

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9
Q

What kind of blood do superior cerebral veins receive? Where do they drain into (3)?

A
  • Deoxygenated blood from cortical surfaces
  • Drain into superior and inferior sagittal sinus, straight sinus, and transverse sinus
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10
Q

What do deep cerebral veins drain? Where do they converge?

A
  • Drain deep structures of brain
  • Converge on internal cerebral veins – inferior sagittal sinus above 3rd ventricle, continue into straight and sigmoid sinuses
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11
Q

Superior and deep cerebral veins join at the confluence of sinuses and empty into the internal ____.

A

Jugular veins

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12
Q

Which sinus receives blood from the frontal, parietal, and occipital veins?

A

Superior sagittal sinus

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13
Q

Which sinus drains the medial aspects of the frontal lobe and cingulate gyri?

A

Inferior sagittal sinus

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14
Q

Which sinus is posterior and superior to the cerebellum?

A

Straight sinus

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15
Q

Which sinus is lateral to the cerebellum and runs in the grooves of the occipital bone and squamous temporal bone?

A

Transverse sinus

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16
Q

The great cerebral vein continues into the ____ sinus, which then drains into the ____ sinus.

A
  • Straight
  • Sigmoid
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17
Q

Function of blood brain barrier (BBB)? (2)

A
  • Protects brain against toxic substances and allows essential nutrients in
  • Protect against abnormal variations in concentration of ions and molecules
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18
Q

What are the 3 cortical arteries? Which one is largest?

A
  1. Anterior cerebral artery
  2. Middle cerebral artery (largest)
  3. Posterior cerebral artery
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19
Q

Where does the anterior cerebral artery start/stop? What does it do?

A
  • Emerges through lateral fissure onto lateral surface of brain
  • Supplies sensory and motor cortices to arms, hands, and face…
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20
Q

Where is the posterior cerebral artery? What does it do?

A
  • Splits from basilar artery to go laterally to inferior temporal lobe and caudally occipital lobe
  • Supplies occipital lobe and inferior temporal lobe, thalamus, midbrain (visual processing, relay station)
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21
Q

What is a cerebrovascular accident?

A

Stroke – brain cells die b/c deprived of oxygen and glucose

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22
Q

What is an occlusive/ischemic stroke? How common are they?

A
  • When something plugs/blocks the artery to prevent blood flow
  • 80-90% of all strokes
23
Q

What is atherosclerosis? What type of stroke does it fall under?

A
  • hardening of artery walls as junk/fat build up (leads to thrombosis or embolism)
  • Occlusive stroke
24
Q

What is a transient ischemic attack? What type of stroke does it fall under?

A
  • temporary interruption of blood flow for a few minutes to an hour
  • Occlusive stroke
25
Q

What is thrombosis? What type of stroke does it fall under?

A
  • complete blockage of blood vessel (most common)
  • Occlusive stroke
26
Q

What is embolism? What type of stroke does it fall under?

A
  • chunk of undissolved substance narrows or plugs a blood vessel
  • Occlusive stroke
27
Q

What is a hemorrhagic stroke?

A
  • bleeding or rupture of blood vessels under pressure
28
Q

What is an extracerebral vs intracerebral hemorrhage?

A
  • Extra = within meninges
  • Intra = within cortex
29
Q

What are the 3 types of extracerebral hemorrhages?

A
  1. Epidural: under skull
  2. Subdural: under dura mater
  3. Subarachnoid: under arachnoid mater
30
Q

What is an aneurism? Is this considered extra or intracerebral?

A
  • Balloon in weakened artery wall which may rupture
  • Intracerebral
31
Q

What is one risk factor for hemorrhagic strokes?

A

High blood pressure

32
Q

What is an arteriovenous malformation? Is it common?

A
  • Present at birth – tangles which may cause seizures/headaches/hemorrhage
  • Rare
33
Q

Diff bw embolism vs thrombosis vs atherosclerosis?

A
  • Embolism = floating clots
  • Thrombosis = full blockage
  • Atherosclerosis = partial blockage
34
Q

functions of meninges? (5)

A
  • Protect the brain
  • Maintain brain in fluid suspension/cushion
  • Hold structures in place during movement
  • Provide nutrients (CSF)
  • Passageway for blood vessels (arachnoid mater)
35
Q

what are the 4 layers of the meninges?

A
  1. skull
  2. dura mater (tough)
  3. arachnoid mater (spider)
  4. pia mater (tender)
36
Q

which layer of meninges makes direct contact w brain’s surface?

A

pia mater

37
Q

which layer of meninges forms sinuses for venous blood drainage?

A

dura mater

38
Q

where is the epidural space?

A

between the outer layer of the dura mater and the inner surface of the skull or vertebral canal

39
Q

where is the subdural space?

A

between the dura mater and the arachnoid mater

40
Q

where is the subarachnoid space?

A

between the arachnoid mater and the pia mater

41
Q

where is CSF located?

A

subarachnoid space + circulates around the brain and spinal cord

42
Q

what is a hematoma?

A

abnormal collection of blood

43
Q

function of ventricles? how many do we have in our brains?

A
  • circulate CSF
  • 4
44
Q

the ventricle system is interconnected to the ____ space thru ____ in the ____ ventricle

A
  • subarachnoid
  • foramen
  • 4th
45
Q

what are the 2 paired lateral ventricles connected by?

A

interventricular foramen

46
Q

where is the 3rd ventricle?

A

diencephalon

47
Q

where is the 4th ventricle?

A

dorsal pons and medulla

48
Q

what are the 3rd and 4th ventricles connected by?

A

cerebral aqueduct

49
Q

what is the CSF produced by?

A

choroid plexus (present in each ventricle)

50
Q

where does CSF drain? how much of it is produced daily?

A
  • into the venous system of the blood supply
  • 500ml a day
51
Q

parts of lateral ventricle? (3)

A
  • anterior horn
  • posterior horn
  • inferior horn
52
Q

CSF absorbs __% of the brain’s weight

A

95

53
Q

T or F: CSF gets reabsorbed

A

true – reabsorbed by arachnoid granulations that dump into sagittal sinus

54
Q

what is hydrocephalus?

A
  • increased fluid and decreased drainage/reabsorption in head
  • results in enlarged ventricles and enlarged cranium, esp in children since fontanelles