neural crest Flashcards
the ___ ___ is called so because it originated at the border between the neural plate and the non neural ectoderm
neural plate
the neural crest gives rise to
PNS, adrenal medulla, melanocytes, facial cartilage, dentine of teeth
the cranial neural crest gives rise to
craniofacial mesenchyme, cranial neurons, glia cells, tooth primordia, cartilage of inner ear
trunk neural crest gives rise to
melanocytes, DRG neurons and schwann cells, sympathetic ganglia, adrenal medulla
vagal and sacral neural crest gives rise to
parasympathetic neurons
a condensation of a mesodorm; occurs in clusters from head to tail; gives rise to vertebrae and axial musculature of the backbone
somite
two major migratory pathways of trunk neural crest
- dorsolateral pathway
- ventral pathway
dorsolateral pathway neural crest does not behave ____
segmentally
ventral pathway neural crest behaves ____
segmentally
the spinal ganglia are segmental and associated with _____
somites
DRG form in the anterior of each ____
somite
the cells in the dorsolateral pathway migrate between dermis and somites; become ____ and colonize skin and hair follicles
melanocytes
the cells of the ventral pathway migrate through the anterior portion of the somites ; give rise to ___
DRG and schwann cells
before the cells begin to migrate the neural crest cells must dissociate from one another and develop proteins necessary for migration which are
a. SLUG (dissociate tight junctions)
b. Rho B (promotes migration)
neural crest cells are ___ early in development (can give rise to many different cells)
pluripotent
