electrical signals Flashcards

1
Q

characterized by temporary change in RMP, strength of it depends on size of stimulus

A

graded potential

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2
Q

stimularion of a neuron reaches a threshold that triggers active transport of ions known as an ___ ____

A

action potential

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3
Q

RMP: actively move ions against gradient; atp dependent

A

pumps

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4
Q

RMP: exchange ions

A

exchanger

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5
Q

RMP: ions to diffuse down concentration gradients when open

A

channels

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6
Q

two major classes of channels

A

leakage and gated

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7
Q

always open; more K+ than Na+ channels
(influx of Na+, efflux of K+)

A

leakage channels

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8
Q

open/closed based on environment

A

gated channels

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9
Q

types of gated channels

A

voltage, ligand, signal, mechanical

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10
Q

more K+ inside and Na+ outside, does what?

A

sets resting membrane potential

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11
Q

RMP results primarily from what three processes

A
  1. diffusion of ions down their conc. gradients (k+ leakage channels)
  2. selective permeability of plasma membrane (3 Na+ out, 2 K+ in)
  3. attraction of cations to anions
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12
Q

gated channel that requires a signal and occurs in cell bodies and dendrites

A

ligand gated

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13
Q

gated channel that requires change in RMP at the initial segment, axon hillock, axon

A

voltage gated

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14
Q

gated channel that is activated by mechanical change and is somatosensory

A

mechanically gated

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15
Q

the magnitude of graded potential can or cannot vary

A

can

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16
Q

this potential spreads passively and is short loved

A

graded

17
Q

ligand gated channels can be ____ tropic or ___ tropic and are activated by extracellular ligand

A

iono or metabo

18
Q

signal at same time but at different synaptic sites

A

spatial summation

19
Q

signal at time back to back on same synapse

A

temporal summation

20
Q

an action potential is started through what type of channel

A

voltage gated

21
Q
A
22
Q

what potential does not decay with distance and magnitude stays the same

A

action

23
Q

ap is spread by

A

simple diffusion

24
Q

action potential requires both ___ and ___ current flow

A

active and passive

25
Q

all voltage gated channels open at _____

A

threshold

26
Q

what ion in action potential has faster reaction time

A

Na+

27
Q

at ___ mV Na closes and K opens

A

+35

28
Q

if there was no myelin the axons would be poor conductors and signals would die out why?

A

current “leaks” out across axon membrane

29
Q

what is the action potential location

A

axon hillock, axon

30
Q

what is the graded potential location

A

dendrites, cell body

31
Q

membrane change in graded potential is either what or what

A

depolarization (excitatory) or hyperpolarization (inhibitory)

32
Q

unmyelinated axons; depolarization/repolarization step-wise and must move down entire membrane

A

continuous conduction

33
Q

node, internode in myelinated fibers, AP passes down nodes, saves ATP (faster)

A

saltatory

34
Q

anesthetics: prolongs inactivation of voltage-sensitive Na+ channel (cannot start another action potential): lidocaine

A

local

35
Q

ketamine is similiar size to magnesium block in NMDA channel and blocks flow

A

intravenous anesthetics