CSF and glymphatic system Flashcards

1
Q

10% of the total fluid volume of the cranial cavity

A

CSF

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2
Q

12% of fluid in cranial cavity; in between cells

A

interstitial fluid

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3
Q

68% total fluid volume ( within cells)

A

intracellular

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4
Q

the body uses ___ system to remove waste from interstital spaces of your tissue

A

lymphatic

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5
Q

several organs are apart of lymphatic system

A

lymph nodes, thymus, spleen, tonsils, peyers patch

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6
Q

attached to brains surface by glial cells called astrocytes

A

pia mater

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7
Q

the lymphatic vessels of the brain are located where

A

meminges

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8
Q

lympathic vessles become extensive at base of brain and exit skull alongside ___ ____

A

cranial nerves

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9
Q

surrounds all exposed surfaces of CNS in subarachnoid space and within ventricles

A

CSF

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10
Q

how is CSF made

A

by specialized ependymal cells of choroid plexus

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11
Q

the blood brain barrier is highly permeable tp

A

water, co2, o2

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12
Q

the bbb is impermeable to

A

plasma proteins and non lipid soluble organic molecules

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13
Q

exceptions to bbb are

A

areas of hypothalamus and pineal gland

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14
Q

substances flow directly into interstitial fluid, tight junctions form between endothelial cells

A

BBB

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15
Q

substances flow from vascular (blood) to plexus; vascular surrounded by chorooid is leaky (cappilaries); tight junctions are formed by choroid plexus

A

BCSF (barrier CSF)

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16
Q

the choroid plexus is ____

A

polarized

17
Q

there is a differential flow of subtabces in BCSF because it is polarized; what is transported in?

A

vitamins, organic nutrients, o2

18
Q

fluid filtered from _____ by choroid plexus

A

blood

19
Q

the CSF flows how

A

lateral ventricles to intraventricular foramen to third ventricle to aqueduct of midbrain to fourth ventricle

20
Q

from the fourth ventricle CSF can flow into ___ ____ of spinal cord out to subarachnoid space

A

central canal

21
Q

small protrusions of arachnoid through the dura mater into superior saggital sinus (venous blood flow)

A

arachnoid granulation

22
Q

generall fluid only flows in one direction

A

from CSF to venous system

23
Q

central blood vessels can chnage blood flow by altering diameter by ____ ___

A

smooth muscle

24
Q

in cappilaries, constriction or dilation is done by ___

A

pericytes

25
Q

CSF flows around a pwathway called ___ ____ space; between atrocyte endfeet becomes continuous with basil lamina and will forced into interstitial space

A

virchow-robin

26
Q

what drives the movement of CSF

A

the heartbeat and smooth muscle/ pericytes surrounding arteries

27
Q

smooth muscles cells surrounding arterioles generate ___ ___ as they contract

A

pulse waves

28
Q

_____ act as carriers for cholesterol

A

apolipoproteins

29
Q

the ___ system is turned off during waking hours

A

glymphatic

30
Q

glymphatic activity ____ during aging

A

decreases

31
Q
A