exam 4 Flashcards

1
Q

what four components does the neural tube become

A

prosencephalon, mesencephalon, rhombencephalon and spinal cord

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2
Q

the prosencephalon during maturation becomes

A

telencephalon and diencephalon

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3
Q

the telencephalon becomes

A

cerebral hemispheres

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4
Q

the diencephalon becomes

A

thalamus

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5
Q

the mesencephalon becomes

A

midbrain

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6
Q

during maturation the rhombencephalon becomes the

A

mesencephalon and myelencephalon

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7
Q

the mesencephalon becomes the

A

pons and cerebellum

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8
Q

the myencephalin becomes the

A

medulla

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9
Q

the ____ condenses at the midline to form notochord

A

mesoderm

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10
Q

the ___ becomes neural plate

A

ectoderm

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11
Q

at the dorsal edge of neural tube the ___ ___ develops

A

neural crest

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12
Q

the neural crest migrates away to give rise to ___

A

PNS

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13
Q

the neural crest becomes what four categories of PNS

A

DRG, autonomic ganglia, adrenal medulla, melanocytes

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14
Q

most common form of cell migration is aided by these cells

A

radial glial cells

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15
Q

what is significant about the reeler phenotype

A

neurons are in the wrong place but adopt appropriate fates by birthdate

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16
Q

what is wrong with the reeler phenotype

A

defective cortical plate, the plate never splits so neurons pile up under plate; yet still reach destination

17
Q

restrict the migration of cells in neural tube and crest; restricts microenvironment the cells are exposed to

A

rhombomeres

18
Q

what are long range cues for growth cones

A

chemorepulsion and chemoattractant

19
Q

what are short range cues for growth cones

A

contact repulsion and contach attraction

20
Q

actin net assembly at + end; net disassembly at - end

A

treadmilling

21
Q

only DCC receptor axons are attracted to

A

netrin

22
Q

repulsive when ____ interacts with robo receptors

A

slit

23
Q

DCC gets silenced by ____ on robo which silences growth cone

A

CC1

24
Q

spontaneous ___ waves in developing neurons are individual of visual stim. and the info conveyed to LGN of thalamus to the cortex

A

Ca2+

25
Q

monocular deprivation in early cortical development leads to a loss of ____ associated w/ closed eye

A

cortex

26
Q

release of cytochrome c revolves around what?

A

formation of pores of mitochondria

27
Q

when NGF is present what happens

A

cell survives

28
Q

anti-apoptotic proteins

A

bcl2/bclw,bcxl

29
Q

pro-apoptotic proteins

A

bax/bak/bid/bad