exam 4 Flashcards
what four components does the neural tube become
prosencephalon, mesencephalon, rhombencephalon and spinal cord
the prosencephalon during maturation becomes
telencephalon and diencephalon
the telencephalon becomes
cerebral hemispheres
the diencephalon becomes
thalamus
the mesencephalon becomes
midbrain
during maturation the rhombencephalon becomes the
mesencephalon and myelencephalon
the mesencephalon becomes the
pons and cerebellum
the myencephalin becomes the
medulla
the ____ condenses at the midline to form notochord
mesoderm
the ___ becomes neural plate
ectoderm
at the dorsal edge of neural tube the ___ ___ develops
neural crest
the neural crest migrates away to give rise to ___
PNS
the neural crest becomes what four categories of PNS
DRG, autonomic ganglia, adrenal medulla, melanocytes
most common form of cell migration is aided by these cells
radial glial cells
what is significant about the reeler phenotype
neurons are in the wrong place but adopt appropriate fates by birthdate
what is wrong with the reeler phenotype
defective cortical plate, the plate never splits so neurons pile up under plate; yet still reach destination
restrict the migration of cells in neural tube and crest; restricts microenvironment the cells are exposed to
rhombomeres
what are long range cues for growth cones
chemorepulsion and chemoattractant
what are short range cues for growth cones
contact repulsion and contach attraction
actin net assembly at + end; net disassembly at - end
treadmilling
only DCC receptor axons are attracted to
netrin
repulsive when ____ interacts with robo receptors
slit
DCC gets silenced by ____ on robo which silences growth cone
CC1
spontaneous ___ waves in developing neurons are individual of visual stim. and the info conveyed to LGN of thalamus to the cortex
Ca2+
monocular deprivation in early cortical development leads to a loss of ____ associated w/ closed eye
cortex
release of cytochrome c revolves around what?
formation of pores of mitochondria
when NGF is present what happens
cell survives
anti-apoptotic proteins
bcl2/bclw,bcxl
pro-apoptotic proteins
bax/bak/bid/bad