Nervous System Flashcards
Nervous system
Responsible for controlling most body functions, receive and respond to external and internal environmental stimuli
Central and peripheral
Neurons
Functional units of the nervous system
Convert stimuli into electrochemical signals and conduct them through the body
Elongated cell consisting of dendrites, cell body, and axon
Dendrites
Cytoplasmic extensions that receive info and transmit it toward the cell body
Cell body
Soma
Contains the nucleus and controls the metabolic activity of the neuron
Axon
Long cellular process that transmits action potentials
Myelin
Insulating substance preventing leakage of signal from the axons
Increases conduction velocity
Nodes of Ranvier
Gaps between segments of myelin
Where action potential propagates through saltatory conduction
Oligodendrocytes
Glial cells that myelinate CNS axons
Provide structural framework for the CNS
Synapse
The gap between the axon terminal of one cell and dendrites of the next cell
CNS cells
Astrocytes, oligodendrocytes, microglia, ependymal cells
PNS cells
Satellite cells, Schwann cells
Astrocytes
Maintain the integrity of the blood-brain barrier
Regulate nutrient and dissolved gas concentrations
Absorb and recycle neurotransmittes
Microglia
Remove cellular debris and pathogens
Ependymal cells
Line the brain ventricles and aid in the production, circulation, and monitoring of cerebral spinal fluid
Satellite cells
Surround the neuron cell bodies in the ganglia
Schwann cells
Enclose the axons in the PNS
Aid in myelination of some peripheral axons
Resting potential
The potential difference at rest between the extracellular and intracellular space due to unequal distribution of ions
-70 mV
Due to Na+/K+ pump and facilitated diffusion of K+ out of the cell
Depolarization
The inside of the cell becomes more positive
Na+/K+ pump
Active transport
Pumps 3 Na+ out of the cell for every 2 K+ in
Results in negative internal environment
Action potential
- Voltage-gated Na+ channels open in response to depolarization to threshold potential (-55 mV)
- Na+ rush down electrochemical gradient into the cell. Further depolarization
- Causes next portion of axon to depolarize. Continues along the axon
- At synaptic terminal, voltage-gated Ca2+ channel opens, Ca2+ rushes in and triggers exocytosis of synaptic vesicles
- Repolarization. High voltage causes voltage-gated K+ channels to open, rushing out of the cell. Na+ channels close. Cell returns to negative potential
Hyperpolarization
Neuron’s voltage shoots past resting potential and becomes more negative due to K+ channels being open
Refractory period
After an action potential during which new action potentials are very difficult to initiate due to hyperpolarization
Ensure forward movement
All-or-none response
If and only if the threshold membrane potential is reached, an action potential with a consistent size and duration is produced
Intensity is coded by the frequency of action potentials not magnitude
Effector cells
Postsynaptic cells other than neurons than neurons communicate with
Neurotransmitter
Chemical messengers that diffuse across the synapse and act on receptor proteins embedded in the postsynaptic membrane leading to depolarization and firing of an action potential
Removed by reuptake, degradation or diffusion
Afferent neuron
Carry sensory info about the external or internal environment to the brain or spinal cord
Efferent neuron
Carry motor commands from the brain or spinal cord
Interneuron
Participate only in local circuits
Link sensory and motor neurons in the brain and spinal cord
Plexus
A network of nerve fibers
Ganglia
Clusters of neuronal cell bodies in the PNS
Nuclei
Clusters of neuronal cell bodies in the CNS
Brain
Mass of neurons
Interpret sensory info, form motor plans, and cognitive function