Developmental Biology Flashcards
Embryology
The study of the development of a unicellular zygote into a multicellular organism
Cleavage
A series of rapid mitotic divisions
Increase cell number without corresponding growth in cell protoplasm
Increase SA:ratio, improving gas and nutrient exchange
Morula
A solid ball of embryonic cells
Blastulation
Begins when the morula develops a fluid-filled cavity (blastocoel) which becomes a hallow sphere (blastula)
Blastula
A hallow sphere of cells
Stage of implantation
Ectopic pregnancy
The embryo implants outside the uterus
Gastrulation
After 2 weeks the embryo is fully implanted in the uterus and transforms from a single cell layer blastula into a gastrula
Gastrula
A 3-layered structure
Ectoderm, endoderm, mesoderm
Ectoderm
Integumentary system (epidermis, hair, nails, epithelium of the nose, mouth and anal canal), lens of the eye, retina, nervous system
Endoderm
Epithelial linings of the digestive and respiratory tracts (lung) and parts of the liver, pancreas, thyroid, and bladder lining
Mesoderm
Musculoskeletal system, circulatory system, excretory system, gonads, connective tissue, portions of digestive and respiratory organs
Neurulation
Regions of the germ layers begin to develop into a rudimentary nervous system before week 3
Notochord
Rod of mesodermal cells that develops along the longitudinal axis of the embryo just under the dorsal layer of ectoderm
Inductive effect on the ectoderm causing it to bend inward and form a groove along the dorsal surface
Neural dorsal ectoderm folds on either side of the groove and fuse, forming a closed tube which gives rise to the brain and spinal cord
Once formed, it detached from the surface ectoderm
Neural crest cells
Cells at the tip of each neural fold of the notochord
Migrate laterally
Give rise to components of the peripheral nervous system (sensory ganglia, autonomic ganglia, adrenal medulla, Schwann cells)
Organogenesis
The body organs begin to form
The cells interact, differentiate, change physical shape, proliferate, and migrate
Growth
The organs increase in size. The continual process from infancy through childhood to adulthood
Gametogenesis
Eggs and sperm develop which permits reproduction to occur