NERVOUS SYSTEM Flashcards
Nervous system
Body’s command centre originating from the brain and controlling thoughts, movement and automatic responses
Central nervous system
Composed of the brain and spinal cord. The brain is contained within the cranial cavity of the skull, and the spinal cord is contained within the vertebral cavity of the vertebral column
Peripheral nervous system
Everything outside of the central nervous system; made up of nerves that branch off from the spinal cord and extend to all parts of body (ganglion & nerves)
Cerebrum (CNS) divisions (2)
Cerebral cortex, basal nuclei
Diencephalon (CNS) divisions (4)
Thalamus, hypothalamus, epithalamus, subthalamus
Brain stem (CNS) divisions (3)
Midbrain, pons, medulla
Division of CNS with no extensions on the slide lol iykyk
Cerebellum
Ganglia (PNS) divisions (2)
Sensory ganglia, autonomic ganglia
Nerves (PNS) divisions (2)
Cranial nerves, spinal nerves
Division of PNS with no extensions iykyk
Enteric Nervous System
Nervous tissue
The nervous tissue in the CNS and PNS contains two basic cell types; neurons and glial cells
Neurons
Involved in communicative function of the nervous system
Glial cells
Provides framework of tissues that supports the neurons and their activities
Neuron structure
Soma/cell body, dendrites, axon
Soma/cell body
Contains nucleus, has most cytoplasm, organelles and connects to dendrites, which bring information into the neuron, and the axon
Dendrites
Branches off cell body and appear as thin extensions. They receive most of the input from other neurons and carry the signals to cell body
Axon
Extends from the cell body and is the process that connects the neuron with its target. They carry electrical impulses that are the means of communication within the brain and between the brain and the rest of the body
Extensions on neurons
Called processes
Polarity of neurons
Neurons are polar because information flows in one direction
Axon hillock
Special region where the axon emerges from the soma where the cell tapers
Myelin sheath
Lipids insulating the axon that facilitates the transmission of electrical signals across axon (phospholipids of the glial cell membrane)
Nodes of ranvier
Gaps on the axon that are NOT insulated by myelin. Contains sodium and potassium ion channels allowing the action potentials to travel down the axon quickly jumping from one node to the next
Axon segment
Length of axon between each gap that is wrapped in myelin
Axon terminal
End of an axon where there are usually several branches extending towards the target cell
Synapse
End bulbs of the axon terminal that connect neurons and help transmit information from one neuron to another
Gray matter
Outer cortex of brain and region of nervous tissue with cell bodies and dendrites. Not necessarily gray as it can be pinkish because of blood content or even tan depending on how long the tissue has been preserved
White matter
Region of nervous tissue that contains axons insulated by a lipid rich substance called myelin sheath that makes it appear white
Colors of white and gray matter
Colors in white and gray matter are what would be seen in fresh or unstained tissue
Group of neuron cell body (gray matter) terminology CNS/PNS
Group of neuron cell bodies in the CNS is referred to as the nucleus. In the PNS, it is referred to as a ganglion
Bundle of axons (white matter) terminology CNS/PNS
A bundle of axons, or fibers found in the CNS is called a tract. In the PNS, it is called a nerve
Give an example of the different uses of terminology regarding the location of bundle of axons
Axons of the eye are called optic nerves as they LEAVE the eye, but when they are inside the cranium, they are referred to as the optic tract
Basic functions of the nervous system (3)
Sensation –> integration –> response
Divisions of the control of the body (2)
Somatic or autonomic
Sensation
Nervous system receives information from the environment through a stimulus (sensation) and generates appropriate responses (eg. Vision, audition, olfaction, propioception)
Integration
Stimuli is compared with, or integrated with other memories of previous stimuli information and becomes processed (at brain and spinal cord)
Response
Integration combines sensory perceptions and higher cognitive functions such as memories, learning, and emotion to produce a response
2 divisions of a response:
- Somatic nervous system (voluntary response)
- Autonomic nervous system (involuntary response)
- Both are divisions of the PNS
Somatic nervous system
Controls conscious perception and voluntary motor responses; contraction of skeletal muscles
Autonomic nervous system
Responsible for involuntary control of the organ system of the body like homeostasis; contraction of smooth muscles, regulation of cardiac muscle, activation of glands –> Sympathetic system/parasympathetic system
Sympathetic system
Fight or flight response
Parasympathetic system
Rest and digest response
Enteric nervous system
Large part of the PNS and is not dependant on CNS. It is responsible for controlling the smooth muscle and glandular tissue in digestive system
Why is it sometimes valid to consider the enteric system to be a part of the autonomic nervous system
Because the neural structures that make up the enteric system are a component of the autonomic output that regulates digestion
Brain (CNS) (3):
- Perception and processing of sensory stimuli (somatic/autonomic)
- Execution of voluntary motor responses (somatic)
- Regulation of homeostatic mechanism (autonomic)
Spinal cord (CNS) (2):
- Initiation of reflexes from ventral horn (somatic) and lateral horn (autonomic) gray matter
- Pathways for sensory and motor functions between periphery and brain (somatic/autonomic)
Nerves (PNS):
- Fibers of sensory and motor neurons (somatic/autonomic)
Ganglia (PNS) (2):
- Receive and process sensory stimuli.
- Relay motor responses in the autonomic nervous system
Digestive tract (ENS):
- Responsible for autonomous functions and can operate independantly of the brain and spinal cord
Identifying types of neurons (3):
- Shape of neuron and the number of processes attached to cell body
- The names for the neurons are based on the cell’s polarity
- Can be classified on where they are found, who found them, what they do, or the types of chemicals used to communicate
Glial cells (neuroglia/glia)
Other type of cell found in nervous tissue that are supporting cells and their functions are directed at helping neurons complete their functions for communication; 6 types, 4 found in CNS and 2 found in PNS
6 types of glial cells:
- Astrocyte (CNS): Support
- Oligodendrocyte (CNS): Insulation, myelination
- Microglia (CNS): Immune surveillance, phagocytosis
- Ependymal cell (CNS): Create cerebrospinal fluid
- Satellite cell (PNS): Support
- Schwann cell (PNS): Insulation, myelination
Brain function
Person’s conscious experiences, the regulation of homeostasis, and coordination of reflexes are al based on neural activity in the brain
Adult brain regions (4):
- Cerebrum
- Diencephalon
- Brain stem
- Cerebellum
Cerebrum
Makes up most of the brain and is composed of two halves (right and left cerebral hemispheres) and a continuous, wrinkled and thin layer of grey matter that wraps both hemispheres and the cerebral cortex. Functions in memory, emotion, consciousness
Cerebral cortex divisions
Frontal lobe, parietal lobe, temporal lobe, occipital lobe
Gyrus
Ridge of one of the wrinkles on the cerebral cortex
Sulcus
Groove between the two gyri of cerebral cortex
Why is the pattern of the folds of tissues important on the brain
Because it indicates specific regions of the cerebral cortex
Basal nuclei (3):
- Found beneath the cerebral cortex and augment cortical processes
- Some basal nuclei in forebrain serve as primary location for acetylcholine production
- Some basal nuclei control initiation of movement (eg. Keeps an urge to jump or scream during class)
Acetylcholine production
Modulates overall activity of cortex and leads to greater attention to sensory stimuli
Alzheimer’s disease
Associated with a loss of neurons in the cholinergic basal forebrain nuclei leading to memory loss, loss of control thought and language
Diencephalon
Connection between the cerebrum and almost all of the nervous system (except for olfaction - sense of smell). The rest of the brain, spinal cord, PNS all send information to the cerebrum through the diencephalon and output from the cerebrum passes through diencephalon
2 major regions of the diencephalon:
- Thalamus: Collection of nuclei that process and relay information between cerebral cortex and the PNS, spinal cord, or brain
- Hypothalamus: Collection of nuclei inferior and slightly anterior to the thalamus that are involved in regulating homeostasis and being in charge of the ANS and the endocrine system
Epithalamus
Contains pineal gland
Subthalamus
Includes subthalamus nucleus, one of the basal nuclei
Brain stem (4):
- The midbrain and the hindbrain (pons and medulla)
- Emerges from ventral surface of forebrain as a tapering cone that connects brain and spinal cord
- Cranial nerves connect through the brain stem and provide brain with sensory input and motor output associated with head and neck
- The major ascending and descending pathways between the spinal cord and brain (specifically cerebrum) pass through brain stem