Nematode, Cestode - Microbio handout Flashcards
[Pharma]
DOC for ascaris
albendazole
[Pharma]
DOC for Ancylostoma and Necator
Albendazole
[Pharma]
DOC for Trichuris
Mebendazole
[Pharma]
DOC for Enterobius
Pyrantel pamoate
[Pharma]
DOC for strongyloides
Ivermectin
[Pharma]
DOC for capillaria
Albendazole
[Pharma]
DOC for Wuchereria and Brugia
DEC
[Pharma]
DOC for trichnella
Thiabendazole
What is the most common and largest intestinal nematode?
Ascaris
What is the infective stage of ascaris?
Embryonated egg
What is the diagnositc stage of ascaris?
unembryonated egg
Ascaris mature in which part of the body?
lungs
Ascaris turn into adult worm where
Small intestine
Worms that have a lung migration phase?
- Ascaris
- Hookworm
- Strongyloides
What is the diagnostic test to determine ascariasis?
- Direct fecal smear
2. Kato katz technique
____ syndrome
hypersensitivity pneumonitis due to lung migration of Hookworm, Ascariasis, Strongyloides
Loeffler Syndrome
___ are blood sucking nematods, presence of buccal spear in filariform larvaoe
N. americanus
A. duodenale
What is the infective stage of hookworm?
Filariform larvae
What is the diagnostic stage of hookworm?
eggs in feces
Adult hookworm live in preferentially live ____
distal jejunum
[Diagnose]
oval or ellipsoidal with thin shell egg
Hookworm
[Diagnose]
Hookworm with buccal spears of filariform larvae
Ancylostoma with teeth
[Diagnose]
Hookworm with semilunar cutting plates
Necator
What are the chronic effect of hookworm?
Microcytic anemia
Hypoalbuminemia
Tx: Albendazole
___ refers to whipworm
Trichuris trichiuria
What is the infective stage of T. trichiuria?
Embryonated egg
What is the diagnostic stage of T. trichuria?
unembryonated egg
[Diagnose]
barrel-shaped eggs with bipolar plugs; football or chinese lanter
Trichuris
Can cause rectal prolapse
Trichuris trichuria
___ also called pinworm
Enterobius vermicularis
___ is a nematode whose parasite is confined to humans
Enterobius vermicularis
What is the most common STH in developed countries?
Enterobius vermicularis
Tx: Pyrantel pamoate
What is the infective stage of Enterobius vermicularis?
embryonated egg
What is the diagnostic stage of E. vermicularis
eggs on perianal fold
Scotch tape technique is used to detect ____
E. vermicularis
autiinfection can occur
Adult E. vermicularis preferentially establish in which part of the intestine?
Colon (usually in the cecum)
___ refers to appendicitis that is fue to E. vermicularis
Oxyuriasis
___ is an STH that is a facultative parasite
S. stercoralis
Tx: Ivermectin
What is the infective stage of S. stercoralis?
Filariform larvae
What is the diagnostic stage of S. stercoralis?
Rhabditiform larvae
What is the method of diagnosing S. stercoralis wherein the fecal material is incubated in a test tube containing water
Harada-Mori Culture
[Diagnosis]
larva currens, paradoxical asthma, hyperinfection syndrome, duodenitis
S. stercoralis
Tx: ivermectin
__ is the only nematode whose life cycle involves a migratory bird
C. philippinensis
What is the infective stage of C. philippinensis?
Infective larvae
What is the diagnostic stage of C. philippinensis?
Unembryonated egg
[Diagnosis]
Peanut-shaped eggs with flattened bipolar plugs
C. philippinensis
[Diagnosis]
ulcerative and compressive degeneration of enterocytes, leading to severe malabsorption
C. philippinensis
[Diagnose]
Chronic watery diarrhea, edema, wasting, protein-losing enteropathy, hypogammaglobinemia
C. philippinensis
Tx: Albendazole
___ most debilitating nematode infection
Wuchereria and Brugia
[Wuchereria/Brugia]
curved, no terminal nuclei, scrotal edema
Wuchereria
[Wuchereria/Brugia]
Kinky, present in terminal nuclei, elephantiasis
Brugia
What is the infective stage of Wuchereria and Brugia?
3rd larval stage
What is the diagnostic stage of Wuchereria and Brugia?
Microfilaria
[Diagnose]
DEC provocation test
Wuchereria and Brugia
____ bodies
Small epitheloid granulomas composed of aggregates of microfilariae surrounded by acidophilic hyalone material
Meyers-Kouwenaar bodies
Tissue nematode
Trichnella spiralis
What is the infective stage of trichnella?
Encysted larvae
What us the diagnostic stage of Trichnella?
Encysted larvae
[Diagnose]
larvae within striated muscles, elevated CPK
Trichnella
Can be diagnosed: Xenodiagnosis
Diagnosed by xenodiagnosis - T. cruzi
[Diagnose]
larvae within striated muscles, elevated CPK
Trichnella
Can be diagnosed: Xenodiagnosis
Diagnosed by xenodiagnosis - T. cruzi
[Diagnose]
nurse cell
Trichnella
[Diagnose]
a nematode that is viviparous
Trichnella spiralis
___ cycle contributes to the distribution of Trichnella
Sylvatic cycle
[Diagnose]
fever, muscle pain, periorbital edema, eosinophilia, hemorrhagic phenomena
respiratory myositis
Trichnella
Tx: Thiabenzaole
What is the vector of Onchocerca volvulus
Female blackfly (Simulium)
[Diagnosis]
dermal nodules, hanging groin, lizard skin, river blindness
Onchocerca volvulus
What is the leading cause of preventable blindness in sub-saharan africa
Onchocerca volvulus
What is the effect of Onchocerca in the anterior chamber?
Iridocyclitis and Glaucoma
What is the effect of Onchocerca in the limbus?
Sclerosing keratitis
What is the effect of Onchocerca in the choroid and retina?
Atrophy and loss of vision
Mazzotti reaction is seen in what drug?
Diethylcarbamazine
African eye worm is transmitted by __-
deer fly or chryops
Tx: Diethycarbamazine
What is the etiology of guinea fire worm that is transmitted when copepods swallowed in water
Dracunculus medinensis
live worm in skin ulcer
Doc ascaris that can cause ocular larva migrans, uveitis, endophthalmitis
Toxocara canis
Most common cause of parasitic meningitis
Angiostronglyus cantonensis
Most common cause of parasitic meningitis
Angiostronglyus cantonensis
[Trematode]
penetrate the skin, via snail
S. japonicum
[Trematode]
ingested raw crab
P. westermani
[Trematode]
Ingested with raw fish
C. sinensis
[Trematode]
What is the intermediate host of Schistosoma japonicum?
Oncomelania hupensis quadrasi
What is the infective stage of Schistosoma?
Cercariae
What is the diagnostic stage of Schistosoma?
Eggs
S. japonicum is more frequently found in what vein?
superior mesenteric vein draining the small intestine
S. mansoni occurs more often in what vein?
Inferior mesentaric veins draining the large intestine
___ test to diagnose Schistosoma by demonstrating the ovoid egg with small hook
Circumoval Precipitin Test
[Schistosoma Egg]
oval, small lateral spone, small hook or knob
S. japonicum
[Schistosoma Egg]
Elongated with prominent lateral spine
S. mansoni
[Schistosoma Egg]
Elongated, rpounded anterior end and terminal spine.
Found in urine
S. haematobium
Acute disease of schistosoma characterized as itching and dermatitis
swimmers itch
systemic hypersensitivity resembling serum sickness, associated with schistosoma infection
Katayama fever
What area in mindanao has no Schistosoma infection?
misamis oriental
What is the snail that is an intermediate host for P. westermanii
Antemelonia asperata
What is the mountain crab that is an intermediate of P. westermanii
Sundathelphusa philippina
What is the infective stage of P. westermanii?
metacercariae
What is the diagnostic stage of P. westermanii?
unembryonated egg
D-shaped egg
Enterobius vermicularis
[Diagnose]
ovoid, thinner opercular end, thickened abopercular enf
P westermanii
What is the CXR finding of P. westermanii?
ring-shadowed opacity
What are the two asian liver flukes?
- Chlonorchis sinensis
2. Opistorchis vivernini
What is the snail intermediate of chlonorchis?
Parafossarulus
What is the fish intermediate of chlonorchis?
Cyprinidae
What is the infective stage of chlonorchis?
metacercariae
What is the diagnostic stage of chlonorchis?
embryonated egg
What is the stain use to demonstrate the ovoid, melon-like ridges and abopercular proturberance of Chlonorchis?
- Potassium permanganate stain
Inflammatory response of chlonorchis can lead to hyperplasia and fibrosis of the
biliary tract
What CA is associated with chlonorchis?
Cholangiocarcinoma
[Cestodes]
From undercooked pork
T. solinum
[Cestodes]
from undercooked beef
T. saginata
[Cestodes]
from undercooked fish
D. latum
[Cestodes]
from food contaminated with dog fecese
E. granulosus
[T. solinum/ T. saginata]
4 suckers, present rostellum, 5-10 primary UB
T solinum
[T. solinum/ T. saginata]
4 suckers, no rostellum, 15 to 25 primary UB in GP
T. saginata
What is the infective stage of T. saginata?
Cystercerci
What is the infective stage of T. solinum
- Cystercerci
2. Eggs
What is the diagnostic stage of Taenia
Gravid proglottids
__ cause neurocystecosis
T. solinum
___ has 2 sucking grooves for attachment, have operculated eggs, fish and copepods
D. latum
What is the infective stage of D. latum
plerocercoid larvae
What is the diagnositic stage of D. latum
Unembryonated egg
What cestode can cause megaloblastic anemia due to B12 deficiency
D. latum
___ scolex and 3 proglottids; one of the smallest tapeworm
E. granulosis
What is the intermediate host of E. granulosus aside from man?
sheep
What is the definitive host of E. granulosis
dog
What is the infective stage of D. latum?
embryonated egg
What is the diagnostic stage of D. latum?
hydatid cyst
What is the definitive host of E. multilocularis
Foxes
[Diagnose]
Multiloculated cyst, honeycomb vesicle
E. multilocularis
What is the most frequently found tapeworm in developed country
Hymenolepsis nana
[Diagnose]
ingestion of cystercercoid larvae from infected rice or flour beetles?
H. nana
[Diagnose]
Rat tapeworm
H. diminuta
[Diagnose]
Ingestion of rat flea cystercercoid larvae
H. diminuta
Most common tapeworm in dogs and cats
Dipylidium caninum
[Diagnose]
Barrel-shaped proglottids in stool after ingesting dog or cat fleas carrying cystercerci
Dipylidium caninum
What is the DOC for Dipylidium caninum
Niclosamide