NALOXONE (generic name)

Question 1

BRAND NAME OF NALOXONE

Answer 1

BRAND NAME

Narcan

Question 2

DRUG CLASS OF NALOXONE

Answer 2

DRUG CLASS

OpioId Antagonist, Antidote

Question 3

DOSE & ADMINISTRATION OF NALOXONE

Answer 3

D & A
ADULT DOSE: 0.4 - 2 mg SIVP / IM/ IO/ SQ/ ET/ IN. Repeat at 5 minutes intervals to maximum total dose of 10 mg.
PEDI DOSE: 0.1 MG/ kg IV/ IO/ SQ every 2 minute as needed. Maximum total dose of 2 mg.

Question 4

INDICATIONS OF NALOXONE

Answer 4

INDICATIONS
Opiate overdose, complete or partial reversal of central nervous system and respiratory depression induced by opioids, decreased level of consciousness, coma of unknown origin.

Question 5

MECHANISM OF ACTION OF NALOXONE

Answer 5

MECHANISM OF ACTION
Competitive inhibition at narcotic reception sites. Reverse respiratory depression secondary to opiate drugs. Complete inhibits the effect of morphine.

Question 6

CONTRAINDICATIONS OF NALOXONE

Answer 6

CONTRAINDICATIONS

Use with caution in Narcotic-Dependant patients and Neonates of Narcotic-Addicted mothers.

Question 7

ADVERSE EFFECTS OF NALOXONE

Answer 7

ADVERSE EFFECTS
Restlessness, Seizure, Dyspnea, Pulmonary Edema, Tachycardia, Hypertension, Cardiac Arrest, NV, Withdrawal Symptom in Opioid-addicted patients, Diaphoresis

Question 8

PRECAUTIONS OF NALOXONE

Answer 8

PRECAUTIONS

Incompatible with alkaline solutions, acute withdraw syndrome may result in a combative patient.