CLOPIDROGREL ( generic name) Flashcards
1
Q
CLOPIDROGEL brand name
A
BRAND NAME
* Plavix
2
Q
CLOPIDROGEL drug class
A
DRUG CLASS
* Thienopyridine Antiplatelet
3
Q
CLOPIDROGEL indications
A
INDICATIONS
- ST elevation MI (STEMI)
- Moderate to high risk non-ST elevation MI (NSTEMI)
- Acute coronary syndrome
- Substitute for aspirin in patients unable to take aspirin
4
Q
CLOPIDROGEL mechanism of action
A
MECHANISM OF ACTION
* Inhibits platelet aggregation by blocking activation of the glycoprotein IIb / IIIa complex
5
Q
CLOPIDROGEL contraindications
A
CONTRAINDICATIONS
- Active GI bleeding
- Intracraneal hemorrhage
- Known hypersensitivity
6
Q
CLOPIDROGEL adverse effects
A
ADVERSE EFFECTS
- Severe neutropenia
- Thromobic thromobocytopenic purpura (TTP)
- GI hemorrhage
- Cerebral hemorrhage
- Angioedema
- Stevens- Johnson syndrome
- Rash
- Flulike symptoms
7
Q
CLOPIDROGEL precautions
A
PRECAUTIONS
* Nexium and Prilosec (proton pump inhibitors) may inhibit the effects of Plavix
8
Q
CLOPIDROGEL dose and administration
A
DOSE AND ADMINISTRATION * ADULT loading dose of 300 - 600 mg PO * PEDI Not recommended
