ATROPINE SULFATE (Atropine Sulfate)

Question 1

ATROPINE SULFATE brand name

Answer 1

BRAND NAME

* Atropine sulfate

Question 2

ATROPINE SULFATE drug class

Answer 2

DRUG CLASS

* Anticholinergic

Question 3

ATROPINE SULFATE indications

Answer 3

INDICATIONS

• Severe bradycardia
• Organophosphate poisoning
• Nerve agent exposure
• RSI in pediatrics
• Beta blocker and calcium channel overdose

Question 4

ATROPINE SULFATE mechanism of action

Answer 4

MECHANISM OF ACTION

• Inhibits the action of acetylcholine at post-ganglionic parasympathetic neuro-effector sites
• Increases heart rate in symptomatic bradydysrhytmias

Question 5

ATROPINE SULFATE contraindications

Answer 5

CONTRAINDICATIONS

• Tachycardia
• Hypothermic bradycardia
• Unstable cardiovascular status with bleeding and myocardial ischemia
• Narrow angle glaucoma

Question 6

ATROPINE SULFATE adverse effects

Answer 6

ADVERSE EFFECTS

• Drowsiness
• Confusion
• Headache
• Tachycardia
• Palpitations
• N / V
• Pupil dilation
• Dry mouth
• Blurred vision
• Flushed dry hot skin
• Paradoxical bradycardia when given at low doses

Question 7

ATROPINE SULFATE precautions

Answer 7

PRECAUTIONS

* Effects are enhanced by antihistamines, procainamide, quinidine, antipsychotics, benzodiazepines and antidepressants

Question 8

ATROPINE SULFATE dose and administration

Answer 8

DOSE AND ADMINISTRATION
* ADULT
Bradycardia 0.5 mg IV every 3-5 minute as needed not to exceed total dose of 0.04 mg/kg (maximum of 3 mg total)
* PEDI
Bradycardia 0.02 mg/kg IV/IO ( minimum dose of 0.1)