IPRATROPIUM (generic name) ATROVENT (brand name)

Question 1

IPRATROPIUM

Drug Class

Answer 1

DRUG CLASS

Anticholinergic

Question 2

IPRATROPIUM

Indications

Answer 2

INDICATIONS
Persistent Bronchospasm (Asthma), COPD exacerbation

Question 3

IPRATROPIUM

Mechanism of Action

Answer 3

MECHANISM OF ACTION
Inhibits iteration of acetylcholine at a receptor sites of bronchial smooth muscle (in the lungs), resulting in decrease contractility of the bronchial smooth muscle and a decrease in mucous production.

Question 4

IPRATROPIUM

Contraindications

Answer 4

CONTRAINDICATIONS
Hypersensitivity of Ipratropium, atropine, alkaloids, peanuts.
Note: New manufactured has eliminated the contraindication pertaining to peanut and soy allergy.

Question 5

IPRATROPIUM

Adverse Effects

Answer 5

ADVERSE EFFECTS
Headache, dizziness, nervousness, fatigue, tremor, blurred vision, cough, dyspnea, worsening COPD symptoms, tachycardia, palpitations, flushing, MI, dry mouth, NV, GI distress.

Question 6

IPRATROPIUM

Precautions

Answer 6

PRECAUTIONS

No drug interactions reported.

Question 7

IPRATROPIUM

Dose and Administration

Answer 7

DOSE AND ADMINISTRATION
ADULT
250 - 500 mcg (.25 to .5 mg) inhalation with nebulizer every 20 minutes up to 3 times
PEDI
same as adult