MORPHINE ( generic name)

Question 1

MORPHINE brand name

Answer 1

BRAND NAME

• Roxanol
• M.S. Contin

Question 2

MORPHINE drug class

Answer 2

DRUG CLASS

* Opioid analgesic ( schedule II narcotic)

Question 3

MORPHINE indications

Answer 3

INDICATIONS

• Severe CHF
• Acute pulmonary edema
• Chest pain associated with acute MI
• Analgesia for moderate to severe acute and chronic pain

Question 4

MORPHINE mechanism of action

Answer 4

MECHANISM OF ACTION

• Alleviates pain through CNS action
• Suppresses fear and anxiety centers in the brain
• Depresses brain respiratory centers
• Increases peripheral venous capacitance and decreases venous return
• Decreases preload and after load, which decrease myocardial oxygen demand.

Question 5

MORPHINE contraindications

Answer 5

CONTRAINDICATIONS

• Head injury
• Exacerbated COPD
• Depressed respiratory drive
• Hypotension
• Undiagnosed abdominal pain
• Decreased LOC
• Suspected hypovolemia
• Patients who have taken MAOIs within 14 days

Question 6

MORPHINE adverse effect

Answer 6

ADVERSE EFFECT

• Confusion
• Sedation
• Headache
• CNS depression
• Respiratory depression
• Apnea
• Bronchospasm
• Dyspnea
• Hypotension
• Syncope
• Bradycardia
• Tachycardia
• N / V
• Dry mouth

Question 7

MORPHINE precautions

Answer 7

PRECAUTIONS

• Potentiate sedative effects of phenothiazines’s (promethazine)
• CNS depressants may potentiate effects
• MAOI’s may cause paradoxical excitation

Question 8

MORPHINE dose and administration

Answer 8

DOSE AND ADMINISTRATION
* ADULT:
STEMI 2 - 4 mg SIVP repeat dose 2 - 8 mg at 15 minute intervals.
PAIN CONTROL ( medical direction)
* PEDI:
0.1 - 0.2 mg / kg IV/IO/IM/SC with MAX dose of 5 mg