ALBUTEROL (generic name) PROVENTIL/VENTOLIN (brand name)

Question 1

ALBUTEROL

Drug class

Answer 1

DRUG CLASS

Sympathomimetic

Question 2

ALBUTEROL

Indications

Answer 2

INDICATIONS
Treatment of bronchospasm in patients with reversible obstructive airway disease (COPD, asthma). Prevention of exercise-induced bronchospasm.

Question 3

ALBUTEROL

Mechanism of Action

Answer 3

MECHANISM OF ACTION
Selective beta-2 agonist that stimulates adrenergic receptors of the sympathomimetic nervous system. Results in smooth-muscle relaxation in the bronchial tree and peripheral vasculature.

Question 4

ALBUTEROL

Contraindications

Answer 4

CONTRAINDICATIONS

Hypersensitive, tachycardia, dysrhythmias, especially those caused by digitalis. Synergistic with other sympathomimetic.

Question 5

ALBUTEROL

Adverse effects

Answer 5

ADVERSE EFFECTS
Headache, fatigue, lightheadedness, irritability, restlessness, aggressive behavior, pulmonary edema, hoarseness, nasal congestion, increased sputum, hypertension, tachycardia, dysrhythmias, chest pain, palpitations, NV, dry mouth, epigastric pain, and tremors.

Question 6

ALBUTEROL

Precautions

Answer 6

PRECAUTIONS

TCA’s may potentate vasculature effects, Beta blockers will antagonize effects, may cause hypokalemia

Question 7

ALBUTEROL

Dose and Administration

Answer 7

DOSE AND ADMINISTRATION
ADULT
2.5 mg dilute in 3 ml NS nebulizer over 10-15 minutes
PEDI
<20 Kg - 1.25 mg/dose via hand held nebulizer or mask over 20 minutes
PEDI
>20 kg - 2.5 mg/dose via hand held nebulizer or mask over 20 minutes