EPINEPHRINE 1 : 10,000 and 1 : 1,000 (generic name)

Question 1

BRAND NAME OF EPINEPHRINE

Answer 1

BRAND NAME

Adrenaline

Question 2

DRUG CLASS OF EPINEPHRINE

Answer 2

DRUG CLASS

Sympathomimetic

Question 3

DOSE & ADMINISTRATION OF EPINEPHRINE

Answer 3

D & A
ALLERGIC REACTION & ASTHMA: 0.3 - 0.5 mg IM/SC 1:1,000
CARDIAC ARREST ADULT: 1mg 1:10,000 IV/IO q 3-5 minute
BRADYCARDIA: 2-10 micrograms/minute infusion
PEDIATRIC ALLERGIC REACTION: 0.01 mg/kg of a 1:1,000 IM/SC with MX of 0.3 mg
PEDIATRIC CARDIAC ARREST: 0.01 mg/kg of 1:10,000 q 3-5 minute MAX single DOSE 1 mg

Question 4

INDICATIONS OF EPINEPHRINE

Answer 4

INDICATIONS
Cardiac Arrest, Symptomatic Bradicardia refractory to Atropine and pacing, Severe hypotension secondary to bradycardia and pacing, allergic reaction, anaphylaxis, asthma.

Question 5

MECHANISM OF ACTION OF EPINEPHRINE

Answer 5

MECHANISM OF ACTION
Alpha and Beta Agonist (some alpha more beta).
Beta 1= +inotropic, chronotropic, dromotropic (Increase HR and cardiac contractility)
Effects. Beta 2=Bronchial smooth muscle relaxation

Question 6

CONTRAINDICATIONS OF EPINEPHRINE

Answer 6

CONTRAINDICATIONS

Hypertension, Hypothermia, Pulmonary edema, Myocardial ischemia, Hypovolemic shock

Question 7

ADVERSE EFFECTS OF EPINEPHRINE

Answer 7

ADVERSE EFFECTS
Nervousness, restlessness, headache, tremor, pulmonary edema, dysrhythmias, chest pain, hypertension, tachycardia, N/V, anxiety.

Question 8

PRECAUTIONS OF EPINEPHRINE

Answer 8

PRECAUTIONS
Inactivated by exposure to sunlight and alkaline solutions. MAOI’s may potentiate effects.
Beta blockers will blunt (mitigate) effects