Naftali Energy 7 Flashcards
How does PPAR gamma effect fat cells
Induce adipogenesis
What are obesogenes
Factors in our environment that Induce obesity
What are EDC’s? (Endocrine disrupting chemicals)
Obisogens that are present in our environment and promote obesity
Which factor obesogens activates
PPAR gamma
Polymorphism in which gene can contribute to hypothalamic inflammation
MC4R gene
What is the frequency of leptin related mutations
Rare
What is FTO gene
Fat mass and obesity association gene
What was the Phenotype of people who carried both alleles for the fat mass and obesity associated Gene
Weighed more
What are are AGE’s
Advanced Glycation Products
harmful compounds that are formed when protein or fat combine with sugar in the blood stream
מפעילים פרופיל פרו דלקתי ופרו טרשתי
How diet Coca-Cola can contribute to the formation of arthearsclerosis
Communicate with a AGE receptors
Which gender has most potential to develop genetic diseases
-
What is intima media thickness
Thickness of the endotel in the arthery (עורק)
האם גורמי הסיכון של טרשת נפוצה פועלים באופן יחידני או סינרגיסטי
סינרגיסטי
יחד גורמים לאפקט מוגבר
What is the most significant risk factor of arthrosclerosis
Glucose level
What are the functions of Apolipoproteins proteins
- Structural role
- Ligand receptors
- guide information of Lipoproteins
- Activators or inhibitors of enzymes involved in metabolism of Lipoproteins
How targeting Receptor NCP1L1 reduce levels of cholesterol
Prevents the circulation of cholesterol from the intestinal lumen to the enterocyte
Which enzyme generates cholesterol Ester from cholesterol
Cholesterol acyl transferase
What is the main product of Chylomicrons
Triglycerides
What the ApoE protein allow to the chylomicron
Bind to LDL receptor
Which Apolipoproteins are available on the chylomicron
Apo a
apo e
apo c
To which compound ApoB is bound?
LDL receptor in the liver
Which Lipo proteins have the smallest volume
HDL
