Biosynthesis Of Triacilglycerol And Phospholipids

Question 1

What is the origin molecule of triacylglycerol and phospholipids?

Answer 1

Glycerol 3 phosphate

Question 2

In which ways we can get glycerol 3 phosphate?

Answer 2

Glycolysis and glyceroneogeneisis

Question 3

What is the origin product of Glyceroneogenesis?

Answer 3

pyruvate, alanine, glutamine

Question 4

In which tissues glycerol kinase is present

Answer 4

Kidneys and liver

Question 5

Does glycerol kinase appear in fat cells

Answer 5

No

Question 6

What is phosphatidic acid?

Answer 6

Phosphatated glycerol with 2 added fatty acids

Question 7

What is the name of glycerol with 2 fatty acids on it

Answer 7

Phosphotidic acid

Question 8

Are there phospholipids that are not based on glycerol?

Answer 8

Yes

Question 9

When we have rapid growth of cells, what do we need more - phospholipids or triacylglycerol?

Answer 9

Phospholipids

Question 10

Which enzyme turns phosphatidic acid to 1,2 di acilglycerol

Answer 10

Phosphatidic acid phosphates

Question 11

What is the main regulation over the process of building triacylglycerol

Answer 11

Level of sugar in our blood

Question 12

Which processes insulin accelerates (Regarding to Acetyl CoA)

Answer 12

Turning pyruvate to Acetyl-CoA

turning acetyl Co-A to fatty acids

Question 13

What can be the Origin of acetal coa

Answer 13

Glucose and ketogenic amino acids

Question 14

People with diabetes can’t (regarding to fats)

Answer 14

Store fats

Question 15

Why can’t diabetes store fats

Answer 15

Because lack of oxaleacetale disable insertion of acetal coa to Krebs cycle

Question 16

How many carbons are there in cholesterol

Answer 16

27

Question 17

How many rings are there in the cholesterol molecule

Answer 17

4

Question 18

Does cholesterol has hydrophilic part?

Answer 18

Yes, one Hydroxyl (OH) group

Question 19

For which purposes cholesterol is needed?

Answer 19

Build membranes and produce essential materials from it

Question 20

How many Acetyl Co-A molecules initiates building of cholesterol

Answer 20

3

Question 21

What is the second product in the clidesterd building process

Answer 21

Mevalonate

Question 22

What is the third product in the cholesterol building process

Answer 22

Isoprene (activated)

Question 23

What is the form of Squalene

Answer 23

Linear

Question 24

Which enzyme actives the committed step in the production of cholesterol

Answer 24

HMG Co-A reductase

Question 25

Where most of the cholesterol is produced in our body

Answer 25

liver cytosol

Question 26

How phosphates effect Hmg coa reductase?

Answer 26

Inactivates it

Question 27

How high levels of cholesterol in the cells effect production of cholesterol?

Answer 27

Inactivation of Hmg coa reductase

Question 28

How high levels of cholesterol in liver cells effect HMG coa reductase?

Answer 28

It is degraded by proteolise of ubiquitin

Question 29

What is cholesteryl ester?

Answer 29

Form of storage for surpass cholesterol

Question 30

How a disease of surpass cholesterol is called

Answer 30

Hypercholesterolemia

Question 31

Which enzyme statins holds back?

Answer 31

Hmg coa reductase

Question 32

How statins lower the level of cholesterol in the blood

Answer 32

- Less cholesterol is produced | - More cholesterol absorbed by the receptors on the cells

Question 33

Which element is harm in the familial hypercholesterolemia gets harmed

Answer 33

LDL receptor

Question 34

Which enzyme turns cholesterol to cholesteryl Esther?

Answer 34

ACAT (acyl-CoA: cholesterol acyltransferase)

Question 35

Which hormone is produced from cholesterol?

Answer 35

Progesterone Testosterone Cortisol

Question 36

What is the origin product of testosterone?

Answer 36

Progesterone

Question 37

What does aldosterone do?

Answer 37

Regulates reabsorbtion of Na+, cl-, HCO3 in the kidney

Question 38

What is the backbone of spingolipids?

Answer 38

Sphingosine

Question 39

How spingosine is different from glycerol?

Answer 39

Has another amine group and chain of 15 Carbons with double bond

Question 40

What is the committed step of producing spinogolipids?

Answer 40

The step that catalyzed by serine palmitoyil coa transferase