הקלטת שיעור קטבוליזם של חומצות שומן חלק ב Flashcards
With help of which co-enzyme mutatse enzyme functions?
B-12
What is the functionality of epimerase?
Stereochemic inversion
What is the functionality of mutase
Replaces 2 functional group from one carbon to other within the same molecule
Why is it impossible to find b-12 on plants?
Because bond between C-N is broken under sunlight
from which intermediate product the breakdown of fatty acids process is influenced
Malonyl-CoA
What is the most regulated process in the fatty acids breakdown?
Replacing CoA with carnitine
What the existence of malonil coa is a signal for?
To build fatty acids
What does the malouyl - con Do to the fatty acid?
Prevant from it to enter the mitochondria
Which function activates Acc!
Taking out its phosphate
Which hormone is secreted when there is low blood glucose?
Glucagone
When act is phosphorilated, how does it influence melonyl coa
Melonyl CoA production is stopped
Is there regulation over b-oxidation inside the mitochondria?
Yes, mild one
Which product in the mitochondria serves as regulators for p-oxidation?
Nadh-enzyme 3
Acetyl CoA
Which product accumulation is a single to enter fatty acids into the muscle?
AMP to AMPK phosphorylation of ACC
What cause high level of NADH
Prevents ß oxidation
What do we have more, ATP or AMP
ATP
How does amp serves as a signal for energy level?
Allostericallyy, via ampk
Which proteins are increased due to signal of glucagonelapinephrine?
CAMP CREB and PPAR alpha
Where does the ketone bodies are produced
In the liver mitochondria
Why can’t excessive acetal coa enter to the Krebs code?
Lack of oxaloacetate
In which 2 cases we produce ketone bodies
- Starvation
2. Type 1 diabetes
Which enzyme is lacking l in case of x cessive gluconeogenesis?
Oxaloacetate
Where does ketone bodies produced?
In the liver
What is the first ketone body that generated
Aceto acetate
What are the unreversed enzymes in the process of Generating ketone bodies?
HMG CoA synthase
HMG CoA lyase
Can the liver break ketone bodies?
No, it only generates them
