Dani Brain 2 Flashcards
How much of our brain is fat
60%
How myelin allowed development of brain in vertebrates
Conducting nerves faster and decrease in size of nerves
Which glial cell produces myelin sheet
Oligodendrocyte
What does the myelin consist off
80% of fat and 20% protein
Which types of protein are Present in the myalin
Proteolipid protein
Myelin basic protein
Myelin oligodendrocyte glycoprotein
Does young children has Myelin
No
Which type of cells generates myalin
Oligodendrocytes and Schwann cells
How many axons does the Schwann cell can cover
1
How many neurons each oligodendrocyte cover
Up to 50 exons
When the myelination process is complete, is there a possibility of production new myelin?
Yes. Through learning new tasks
In which area of the brain, the gray matter is located
In the outer part of the brain
Which cells are considered part of the gray matter of the brain
Axons without myelin
Glial cells
capillary blood vessel
neutrophils
Which type of cells the white matter contained
Oligodendrocytes and strocytes
Which type of matter in the brain consist Myelinated cells
White matter
What does the oligodendrocyte consume as an energy source
Glucose and lactate
Which product can the oligodendrocyte send
Lactate
To witch sub groups we split the myelin related diseases
Loss of myelin and defects in the development of them myelin
Which types of diseases caused due to the Myelination
Multiple sclerosis
Gillian beret syndrome
What ae the Dysmyelination dieseas
Pelizaeus merzbacher Disease
Cannavan disease
Schizophrenia
Which nervous system multiple sclerosis is related to
Central nervous system (CNS)
Which part of the brain cell is damaged during MS
Myelin
Which gender suffers more from multiple sclerosis
Woman
In which race MS is more common
Caucasians
Which groups of fatty acid are present in the brain
Sphingolipids
Phospholipid
Cholesterol
What does the fatty acid function for
Signaling molecules sources of energy
synaptogenesis neurogenesis impulse condition and other
What is the main usage of lipids for the brain
Utilize acylated lipids to generate phospholipids for cell membrane
How leptin affect energy expenditure in the brain
Increase it
How leptin increases the energy expenditure in the brain
Buy acting on hypothalamic centers that increases fatty acids flow
How much of the body cholesterol is located in the brain
I’m about to 25%
Where does the brain cholesterol is produced
In the brain because it cannot cross the brain blood barrier
Which type of cholesterol can cross the blood brain barrier
Very dense HDL
Which regulatory element binding protein regulates the production cholesterol
SREBP2
Which neural cells is the main producer of cholesterol in the brain
Astrocytes
From which material the astrocyte creates myelin
Cholesterol
Which Apolipoproteins is usually impaired in Alzheimer disease
ApoE4
Which type of Apolipoproteins is usually increase in Alzheimer disease
APO E4
