Integration Of Metabolism Flashcards
Which functions needs to be done by the liver in case of a diet rich in protein?
Amino acid catabolism
gluconeogenesis
glycogen breakdown
What functions needs to be done by the I’ver in case of a diet rich in carbohydrates?
Glycolysis , lipids synthesis , glycogen synthesis
What is the main source of the muscle when we perform light activity or rest?
Fatty acids
ketone bodies
And blood glucose
In case of light activity, which hormone is secreted?
Adrenalin
Which glut is activated in case of light activity?
Glut 4
Does the activation of glut 4 is sugar level dependent?
Yes
If there is low level of sugar, Will sugar enter the cells?
No
Why physical activity is good for diabetes
It helps insert sugar to the cells
How does adrenaline influence levels of calcium?
Levels goes up
Which mineral accumulate in case of increased adrenaline?
Calcium
Which enzymes AMP activates in the liver
Enzymes that break down glycogen
In case of intense activity, what is the primary source of energy?
Lactate
Does the body need oxygen to turn lactate into energy?
No
What gives us phosphocreatine ?
Energy
From which molecule we earn more energy,ATP or creatine phosphate?
Creatine phosphate
Why does the creatine yields high-level of energy?
The presence of two nitrogens
In which tissues glut 2 in mostly expressed?
Liver, pancreas, intestine
In which tissues glut 4 in mostly expressed?
Muscles, adipose, heart
How do we get energy from creatine?
Transfer its phosphate to ADP to get ATP
What is the ratio between quantity of enrgy sources to their availability?
Contrast
Does Slow switch fibers contain small amount of mitochondria?
No, it has a lot of them
Which process fast switch is specializes at?
Lactic fermentation
Marathon runners need more slow or fast switch fibers?
Slow swich
Which enzyme is highly present in fast switch fiber muscles?
Lactate dehydrogenase
In which state the glucose Alanin occurs?
Starvation
During Cori cycle, which metabolic process is been stressed in the muscle?
Glycolysis
Which product lS sent out from the muscle to the liver during Cori cycle?
Lactate
Which product is sent out from the liver to the muscle during Cori cycle?
Glucose
Why do we want to turn pyruvate to lactate during glycolysis?
To earn nad+
How turning pyruvate to lactate helps us to do glycolysis?
Because we get more nad+ who is essential for step 6 of glycolysis
In case of starvation, who is the first that we want give glucose to
Brain
How can we utilize alpha keto acid?
Insert to krebs cycle, In the muscle or make acetyl CoA
Which reaction alanine aminotrasterase catalyzes?
Glutamate transfer its amine to pyruvate to get alanine
In wich tissue we are able to find a lot of alanine aminotransterase
In the muscle
What is the end product of gluconeogenesis?
glucose
What are the sources of pyruvate in gluconeogenesis?
Lactate and alanine from the muscle
What are the sources of gluconeogenesis?
Lactate, alanine, glutamine, glycerol
Can we get glucose from fatty acids
No
To which product ketogenic amino acid break?
Acetyl CoA
What is the major energy source of the liver
Fatty acids
How can we use acetyl coa
Energy (krebs cycle), ketone bodies, build fatty acids
How many acetyl coa are there in the original of ketone bodies
2
What is the by product of generating ketone bodies
Acetone
Does Keto acyl transfer is present in the liver
No
Which enzyme breaks down keto bodies and does not present in the liver
Beta ketoacyl coa transferase
