Myocardial Infarction Flashcards
When does acute coronary syndrome occur
when the heart tissue endures prolonged ischemia without recovery
How is acute coronary syndrome classified
STEMI or nonSTEMI
STEMI heart attack
elevated ST, damage goes through the entire cardiac wall
nonSTEMI heart attack
depressed ST, damage does not go through the entire cardiac wall (subendocardial)
When does myocardial infarction begin
with coronary artery atherosclerosis with causes obstruction then ischemia
What are the ways an obstruction can occur
ruptured plaque attracts platelets, which then forms a thrombus
What can result if coronary artery blood supply remains constant but myocardial demands increase
severe hypertension, left ventricular hypertrophy
Risk factors
atherosclerosis, hyperlipidemia, diabetes, hypertension, smoking, family history
What is the extent of damage influenced by
location/level of occlusion in coronary artery, length of time the coronary artery is occluded, and heart’s availability of collateral circulation
Womens s/s
SOB, sweating, nausea, vomiting, ingestion, panic/anxiety
Diagnostic tests
ECG, blood tests, echocardiogram, coronary angiography
Blood tests
CPK-MB fraction, troponin 1
Why are blood tests used
when heart cells die, intracellular contents spill into the bloodstream
Troponin 1
a cardiac protein highly specific for cardiac muscle necrosis released only when myocardial cell death has occured
When does troponin increase
cell death