Mutations & Meiosis Flashcards
Mutations
Changes in DNA sequence
Additon mutations
Where one or more bases are added to the DNA sequence.
E.g. ATCGTT → ATCCGTT
Deletion mutations
Where one or more bases are removed from the DNA sequence.
E.g. ATCGTT → ATCTT
Substitution mutations
Where one or more bases are changed in the DNA sequence.
Mutation agents
ncrease the rate at which mutations occur.
Mutagenic agents include:
Chemicals (e.g. bromine and benzene).
Exposure to ionising radiation and ultraviolet radiation.
Non-Disjunction Mutations
mutations in the number of chromosomes in the cells.
Meiosis
A type of cell division that produces four genetically different daughter cells (gametes) with a haploid number of chromosomes. It involves two divisions.
Haploid
Have half the number of chromosomes as diploid cells).
Diploid
An organism with two copies of every chromosome
What is the term to describe an organism that has two copies of every chromosome?
A diploid organism
Steps of meisosis include:
- Chromosomes replicate to produce sister chromatids
- Chromosomes condense to form a double-armed chromosome
- Chromosomes are arranged in the center of the cell
- Chromosomes in a homologous pair are separated
- The cell divides and one chromosome from each pair is in each daughter cell
- The sister chromatids are separated
Homologous pairs
chromosomes with identical genes but different alleles
What does meisosis II produce?
Four genetically different haploid cells
What is the process of separating chromosomes into random combinations?
Independent segregation