Biological membranes Flashcards
Cholestrol
- present to make the membrane more rigid and reduce the lateral movement of the
phospholipids.
-prevents the leakage of water and dissolved ions from the cell as it is very hydrophobic.
Intrinsic proteins
These may be integrated throughout the membrane. Intrinsic proteins
- include carrier proteins which allow
substances to cross the membrane.
Extrinsic proteins
On the surface of the membrane
Proteins
present to aid movement across the membrane, provide mechanical support and act in conjunction with glycolipds as receptors.
Glycolipds
- These are made up of a carbohydrate that is bound to lipids.
- These extend from the surface of the cell
- acts as a cell surface receptors for certain molecules.
- They also allow cells to adhere to one another to form tissues.
Glycoproteins
- These are carbohydrates that attach to extrinsic proteins and acts a cell surface receptors and
neurotransmitters. - These allow cells to recognise one another as well as attach to form tissues.
What is the main function of plasma membranes
Defines the borders of cells and most organelles.
-is selectively permeable. means that the membrane allows some materials to freely enter or leave the cell/organelle, while other materials cannot move freely.
The rate of gas exchange by diffusion becomes more rapid as:
- The surface area of the surface increases
- The diffusion distance decreases
- The diffusion gradient becomes more steep
- The temperature increases
Structure of a phospholipid
- consist of glycerol, two fatty acids, and a phosphate-linked head group.
- The hydrophilic phospholipid head faces outwards and the hydrophobic fatty acids faces inwards
Structure of cholestrol
a lipid that sits with phospholipids in the core of the membrane.
Thickness of phospholipid
The molecules arrange themselves into a bilayer which ranges from 5 to 10 nm in thickness.
What factors affect permeabiity of cells?
Temperature
pH
Solvent concentration
Permeability
How easy it is for substances to pass through
One type of mutation in the CFTR protein prevents the transport of chloride ions through the channel.
Which of the following is most likely to be observed in the lungs of patients with this mutation?
Sticky mucus with high electryote concentration
Why do phospholipids tend to spontaneously orient themselves into something resembling a membrane?
Phospholipids are amphipathic molecules. The polar head faced towards the water and the non polar fatty acid tails face towards other fatty acid tails
Why is it advantageous for the plasma membrane to be fluid in nature?
Fluidity allows greater flexibility to the cell and motion of membrane components required for transport
Explain why glucose cannot pass directly through the cell membrane.
The plasma membrane is selectively permeable to polar molecules, a transport protein is required for larger molecules.
List 3 biological molecules which might be found in the plasma membrane.
Phospholipids
Cholestrol
Protein Or Carbohydrates
In which cell type is cholesterol found in the plasma membrane?
Eukaryotes
What organism is often used in experiments to measure membrane permeability through the release of its pigment?
Beetroot
What effect would increasing temperature have on the permeability of the plasma membrane?
Increase