Inheritance Flashcards

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1
Q

Genotype

A

The genetic constiution of an organism.

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2
Q

Phenotype

A

The expression of an organim’s genetic constitution, combined with its interaction with the enviroment.

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3
Q

Allele

A

Different forms of a particular gene found at the same locus (position) on a chromosome. A single gene could have many alleles.

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4
Q

How many alleles per gen do diploid organims carry?

A

2

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5
Q

What is meant by a dominant allele?

A

An allele whose characteristic will always appear in the phenotype, whether one or two are present.

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6
Q

What is it meant by a recessive allele?

A

An allele whos characteristic only appears in the phenotype if no dominant allele is present, meaning two must be present.

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7
Q

What is meant by a codominant allele?

A

Two dominant alleles that both contribute to the phenotype, either by showing a blend of both characteristics, or the characteristics appearing together.

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8
Q

What is meant by homozygous and heterozygous?

A

Homozygous = both allelles are domoninant or both alleles are recessive.

Heterozygous = one allele is dominant the other is recessive

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9
Q

Monohybrid inheritance

A

Where one phenotypic characterstic is controlled by a single gene.

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10
Q

Draw a Punnet square to show a monohybrid cross with parental genotypes of GG and gg.

What % of these offspring will express the characteristic determined by allele G?

A

Check Physics maths tutor flashcard.

Q2. 100%

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11
Q

Draw a Punnet square to show a monohybrid cross with parental genotypes of Gg and Gg.

What % of these offspring should express the characterstic determined by allele G?

A

Check PM flahcards

Q2. 75%

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12
Q

Draw an example of a genetic diagram

A

Check PM Flashcard

Make sure to include:
Parent phenotypes
Parental genotypes
Gametes
Offspring genotype (punnet square)
Offspring phenotype = ratio
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13
Q

Define dihybrid inheritance

A

Where two phenotypic characteristics are dtermined by 2 different genes present on 2 different chromosomes at the same time.

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14
Q

Draw a Punnet square to show a dihybrid cross with parental genotypes of RrGg and RrGg.

How many of these offspring should have the same phenotype as their parents

A

Refer to PM flashcard

Q2. 9/16
6 will math their parents on one characteristics, but differ on the other
1 will differ on both characteristics

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15
Q

What is meant by sex-linkage

A

Where an allele is located on ne of the sex chromomsomes, meaning its expression depends on the sex of the individual

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16
Q

Why are male more likely to express a recessive sex-linked allele?

A

Most sex-linked alleles are located on the X chromosome. There males only get one copy of the allele, so will express this characterstic even if its recessive. Since female get 2 alleles, this is less likely.

17
Q

Which parent do males inherit sex-linked characteristics from?

A

Their mother, since the Y chromosome can only come from their father. Therefore the mother is heterozygous for sex-linked alleles, she is a carrier and may pass on the trait on.

18
Q

Draw a punnet square to show a sex-linked cross with parental genotypes of Xᴴ Xʰ and XᴴY

Describe the four possible phenotypes of these offspring

A

Refer to PM flashcard

Q2. Normal female, carrier female, normal male, affected male

19
Q

What is it meant by autosomal linkage?

A

Where two or more genes are located on the same (non-sex) chromosome. In this case, only one homologous pair is needed for all four alleles to be present. For genes that arent linked, two homologous parents are needed.

20
Q

Draw a Punnet square to show a multiple alleles cross with parental genotypes of IᴬIᴼ and IᴮIᴼ.

A

Refer to PM flashcard

21
Q

If Iᴬ and Iᴮ are codomoninant and Iᴼ is recessive, which alleles could the offspring express?

A

AB, A, B, O

22
Q

What is meant by epistasis?

A

Where two non-linked genes interact, with one gene either masking or supressing the other gene

23
Q

What are the two types of epistasis?

A

Recessive epistasis = where two homozygous recessive alleles mask expression of another allele.

Dominant epistasis = where one dominant allele masks expression of multiple other alleles.

24
Q

Draw a Punnent square to show an epistsis cross with parental genotype of AABB and aabb.

Genotypes BB or Bb allow expression of gene A, while genotype bb masks gene A. With this in mind, what % of the offspring will have gene A masked>

A

25%

25
Q

What is the chi-squared test.

A

A stastical test to finf out whethet the difference between observed and expected data due to chance or real effect.

26
Q

What are the 4 criterias of the chi-squared test?

A
  • Data placed in discrete categories
  • Large sample size
  • Only raw count data allowed i.e. not perecentages
  • No data values equal 0
27
Q

How is a chi-squared test perfomed

A
  • The formula results in a number, which is them compared to a critical value (for the corresponding degrees of freedom).
  • If the number is greater than or equal to the critical value, we conclude there is a significant different between the observed and expected data an that the results did not occur due to chance.
28
Q

How can we use a chi-squared test in relation to the content of this topic?

A

We can compare expected phenotypic ratios with observed ratios to test our understanding of how different genes and alleles are inherited.