Absorption Flashcards

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1
Q

What are micelles?

A

Micelles are circular formations that are made up of phospholipid tails.

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2
Q

Where are sodium-dependent co-transporter proteins located?

A

The epithelial cell membrane

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3
Q

Describe the formation of micelles.

A

After larger, lipid molecules have been broken down into monoglycerides and fatty acids, bile salts are secreted by the liver. The bile salts associate with the monoglycerides and fatty acids to form micelles.

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4
Q

What substances are secreted by the liver to form micelles?

A

Bile salts.

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5
Q

What happens to the co-transporter proteins when amino acids or monosaccharides bind?

A

Conformational change

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6
Q

How are monosaccharides transported into the epithelial cells in the ileum?

A

Using transporter cells

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7
Q

Where is lipase produced?

A

The pancreas

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8
Q

Where are bile salts produced?

A

In the liver.

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9
Q

What is the process of forming micelles called?

A

Emulsification.

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10
Q

In which organs does the digestion of proteins take place?

A

Small intestine & The stomach

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11
Q

What enzymes catalyse the hydrolysis of peptide bonds at the ends of proteins?

A

Exopeptidases

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12
Q

Describe the active transport of sodium ions into the blood

A
  1. Sodium-dependent co-transporter proteins are located in the epithelial cell membranes.
  2. The co-transporter proteins actively transport sodium ions into the blood.
  3. This causes the concentration of sodium ions in the epithelial cells to decrease.
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13
Q

What substances do the bile salts associate with to form micelles?

A

Monoglycerides & Fatty acids

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14
Q

Define digestion.

A

The hydrolysis of large, insoluble molecules into smaller molecules that can be absorbed across cell
membranes.

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15
Q

Which enzymes are involved in
carbohydrate digestion? Where are they
found?

A

● Amylase in mouth
● Maltase, sucrase, lactase in
membrane of small intestine

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16
Q

What are the substrates and products of

the carbohydrate digestive enzymes?

A

● Amylase → starch into smaller polysaccharides
● Maltase → maltose into 2 x glucose
● Sucrase → sucrose into glucose and fructose
● Lactase → lactose into glucose and galactose

17
Q

Where are lipids digested?

A

The small intestine

18
Q

What needs to happen before lipids can

be digested?

A

They must be emulsified by bile salts produced by the liver. This breaks down large fat molecules into smaller, soluble molecules called micelles, increasing
surface area.

19
Q

How are lipids digested?

A

Lipase hydrolyses the ester bond between the monoglycerides and fatty acids.

20
Q

Which enzymes are involved in protein

digestion? What are their roles?

A

● Endopeptidases= break between specific
amino acids in the middle of a polypeptide.

● Exopeptidases= break between specific amino
acids at the end of a polypeptide.

● Dipeptidases= break dipeptides into amino
acids.

21
Q

How are certain molecules absorbed into
the ileum despite a negative
concentration gradient?

A

Through co-transport

22
Q

Which molecules require co-transport?

A

Amino acids and monosaccharides

23
Q

Explain how sodium ions are involved in

co-transport.

A

Sodium ions (Na+) are actively transported out of the cell into the lumen, creating a diffusion gradient. Nutrients are then taken up into the cells along with Na+ ions.

24
Q

Why do fatty acids and monoglycerides

not require co-transport?

A

The molecules are nonpolar, meaning they can easily diffuse across the membrane of the epithelial cells.