Cancer Flashcards
What is the common mechanism that causes cancer?
Uncontrolled cell divison
What stages in the cell cycle can be targeted to treat cancer
G1 and S phase in interphase
G1 Phase
a phase in interphase that produces new organelles and causes the cells to grow in size.
S phase
The stage in interphase that causes DNA to replicate.
What phase in interphase produces new organelles and causes the cells to grow in size?
G1
What phase of the cell cycle are the G1 and S phase found in?
Interphase
Mutation
A change in the structure of a gene due to alteration of single base units in DNA resulting in variation
Chemotherapy drugs such as vincristine and colchicines disrupt mitosis by binding to tubulin (the subunit of microtubules) and interfering with microtubule assembly and disassembly.
Exactly what mitotic structure do these drugs target, and what effect would that have on cell division?
A-A* (AO3/4)
The drug binds the tubulin, which leads to an error in the chromosome seperation. This could lead to apoptosis
Which stages of the cell cycle are common targets for anti-cancer drugs?
S and G1 phase