Muscle Tissue Flashcards
Functions of skeletal muscle
- Producing movement
- Maintaining posture and body position
- Supporting soft tissue
- Guarding body entrances and exits
- Maintaining body temperature
- Storing nutrients
Excitability
The ability to receive and respond to stimulus
Contractilicity
The ability of a muscle cell to shorten when stimulated
Extensibility
Stretching movement of a muscle
Elasticity
The ability of a muscle to recoil to its resting length
Composition of skeletal muscle
Skeletal muscle tissue, connective tissue, blood vessels, and nerves
Muscle fibre
Each cell in skeletal muscle tissue is a single muscle fibre
3 layers of connective tissue surrounding muscle tissue
- Epimysium: surrounds entire muscle
- Perimysium: divides skeletal muscle into compartments
- Endomysium: surrounds individual muscle fibres
Fascicle
Bundle of muscle fibres
Elastic connective tissue
- Capillary networks
- Myosatellite cells
- Nerve fibres
Myosatellite cells
Stem cells that help repair damaged muscle tissue
Tendon
Bundle formed by collagen fibres of epimysium, perimysium and endomysium
Aponeurosis
Broad sheet formed by collagen fibres of epimysium, perimysium and endomysium
Are muscle fibres bigger or smaller than normal cells?
A lot bigger
Are muscle fibres uninucleate and multinucleate?
Multinucleate
Myoblasts
Groups of embryonic cells that fuse, forming individual multinucleate skeletal muscle fibres
Sarcolemma
Plasma membrane of a muscle fibre
Sacroplasm
Cytoplasm of the muscle fibre
Transverse tubules
Narrow tubes whose surfaces are continuous with the sarcolemma and extend deep into the sarcoplasm
Sarcoplasmic reticulum
Forms a tubular network around each myofibril
Terminal cisternae
The tubules of the SR enlarge, fuse, and form expanded chambers
Myofibril
Bundles of protein filaments called myofilaments
What causes skeletal muscle fibre contraction?
Active shortening of myofibrils
Composition of myofilaments
Thin filaments (actins) Thick filaments (myosin)
Sarcomeres
Repeating functional units of in myofibril
Composition of thin filaments
F-actin, nebulin, tropomyosin, and troponin
A bands
Dark bands on sacromere: thick and thin filaments
I bands
Light bands on sacromeres: thin filaments only
Sliding-filament theory
H and I bands narrow, zones of overlap widen and Z lines move closer together
Excitable membranes
Plasma membranes that can propagate action potentials
Neuromuscular junction
Synapse between neuron and skeletal muscle fibre
Events at the neuromuscular junction
- Action potential arrives triggering exocytosis of ACh into synaptic cleft
- ACh opens membrane receptors and Na+ rush in to cell, generating action potential in sarcolemma
Excitation-contraction coupling
- Neural control
- Excitation
- Release of calcium ions
- Contraction cycle begins
- Sarcomere shortening
- Generation of mucle tension
Contraction cycle and cross-bridge formation
- Contraction cycle
- Active-site exposure
- Cross-bridge formation
- Myosin head pivoting
- Cross-bridge detachment
- Myosin reactivation
Types of muscle contractions
Isotonic concentric: muscle tension exceeds the load and muscle shortens
Isotonic eccentric: muscle tension is less than load and muscle elongates
Isometric contraction: muscle as a whole does not change length
Anaerobic process
Glycolysis
Aerobic metabolism
Requires oxygen
Types of skeletal muscle fibres
- Fast fibers
- Slow fibers - myoglobin
- Intermediate fibers
Skeletal muscle tissue
Striated, many peripherally located nuclei - voluntary
Cardiac muscle cells
- Striated
- 1 nucleus
- Aerobic metabolism
- Intercalated discs bind sarcolemmas of neighbouring cardiac muscle cells
Smooth muscle tissue
- Non-striated involuntary muscle tissue
- No sarcomeres
- Involuntary