Development and Inheritance Flashcards
Fertilisation
Acrosomes of sperm release hyaluronidase and acrosin which allow them to penetrate the corona radiata and cona pellucida of the oocyte
Oocyte activation
Oocyte completes meiosis II, becoming a mature ovum
Block to polyspermy
Membrane depolarisation and cortical reaction act to ensure only 1 sperm fertilises an egg
Amphimixis
Combining of male and female chromosomes
First trimester
Cleavage subdivides the cytoplasm of the zygote in a series of mitotic divisions, the zygote becomes pre-embryo and then a blastocyst
Implantation
Placentation
Embryogenesis
Implantation
Blastocyst becomes enclosed within the uterine endometrium
Occurs about 7 days after fetilisation as the blastocyst adheres to the uterine lining
Placentation
Occurs as blood vessels form around the blastocyst and the placenta develops
Blastocyst
Outer trophoblast
Inner cell mass
Cytotrophoblast
Inner cellular layer
Ectopic pregnancy
Implantation occurs somewhere other than within the uterus
Gastrulation
Embryonic disc composed of:
Ectoderm
Mesoderm
Endoderm
Embyonic disc becomes a 3 layered sheet
Induction
Chemical interplay among developing cells is induction
Extra-embryonic membranes
Yolk sac, amnion, allantois, and chorion
Yolk sac
Important site of blood cell formation
Amnion
Encloses fluid that surrounds and cushions the developing embryo