Metabolism, Nutrition, and Energetics Flashcards

1
Q

Subtrates

A

Substances acted on by an enzyme

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2
Q

Metabolism

A

Sum of all chemical and physical changes that occur in body tissues

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3
Q

Catabolism

A

Catabolic reactions

Convert large molecules into smaller ones

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4
Q

Anabolism

A

Anabolic reactions

Convert small molecules into larger ones

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5
Q

Nutrient pool

A

All the available nutrient molecules distributed in the blood

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6
Q

Catabolism of fats

A

Lipolysis

Fats > fatty acids and glycerol

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7
Q

Catabolism of carbohydrates

A

Glycogenolysis

Carbohydrates > glucose

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8
Q

Catabolism of proteins

A

Proteins > amino acids

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9
Q

What provides the energy for anabolism?

A

ATP from mitochondria

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10
Q

4 reasons cells synthesise new organic compounds

A
  1. Carry out structural maintenance or repairs
  2. To support growth
  3. To produce secretions
  4. To store nutrient reserves
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11
Q

Energetics

A

Flow of energy and its transformation from one form to another

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12
Q

Oxidation

A

Loss of electrons

Decrease in potential energy

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13
Q

Reduction

A

Gain of electrons

Increase in potential energy

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14
Q

Coenzyme

A

Acts as an intermediary that accepts electrons from one molecule and transfers them to another molecule e.g. NAD and FAD

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15
Q

Cellular respiration

A

glucose + 6 oxygen -> 6 carbon dioxide and 6 water

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16
Q

Glycolysis

A

The cell gains a net 2 molecules of ATP for each glucose molecule broken down anaerobically to 2 molecules of pyruvate. 2 molecules of NADH are also produced. In most cells, electrons are passed from NADH to FAD by an intermediate electron carrier in the intermembrane space, producing FADH2, and then to the electron transport chain

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17
Q

Citric acid cycle

A

Each of the two revolutions of the citric acid cycle required to break down the 2 pyruvate molecules completely yields 1 molecule of ATP by way of GTP. This cycling provides an additional gain of 2 molecules of ATP. This cycle transfers hydrogen atoms to NADH and FADH2. These coenzymes provide electrons to the electron transport chain

18
Q

Electron transport chain

A

For each molecule of glucose broken down, a total of 10 NADH and 2 FADH2 deliver their high-energy electrons to the electron transport chain

Each NADH yields 2.5 ATP and each FADH2 yields 1.5 ATP. The 2 FADH2 molecules from glycolysis yield 3 ATP molecules and 2 water molecules. Each of the 8 molecules of NADH from the citric acid cycle yields 2.5 molecules of ATP and 1 water molecules. Thus, the shuffling from the citric acid cycle to the ETC yields 23 molecules of ATP

19
Q

Gluconeogenesis

A

Formation of new glucose

20
Q

Glycogenesis

A

Formation of glycogen (storage form of glucose)

21
Q

Glycogenolysis

A

Breakdown of glycogen to glucose

22
Q

Glycolysis

A

Breakdown of glucose to pyruvate

23
Q

Beta-oxidation

A

Fatty acid molecules are broken down in a sequence of reactions into 2-carbon acetic acid fragments, and FAD and NAD+ are reduced

24
Q

Lipogenesis

A

Synthesis of lipids

25
Q

Essential fatty acids

A

Must be included in diet

26
Q

How do most lipids circulate the body?

A

Through the bloodstream as lipoproteins

27
Q

Why are lipids important energy reserves?

A

Because their breakdown provides large amounts of ATP

28
Q

Free fatty acids

A

Lipids that can diffuse easily across plasma membranes

Generally bound to albumin

29
Q

Lipoproteins

A

Lipid-protein complexes that contain large insoluble glycerides and cholesterol
A superficial coating of phospholipids and proteins makes the entire complex soluble

30
Q

Groups of lipoproteins

A

Produced in:

Intestines
1. Chylomicrons

Liver

  1. VLDL
  2. LDL
  3. HDL
31
Q

Good cholesterol

A

HDL

Returning from peripheral tissues and doesn’t cause circulatory problems

32
Q

Why does exercise lower cholesterol?

A

Stimulates enzymes that move LDL from the blood into the liver and exercise increases the size of the protein particles that carry cholesterol in the bloodstream

33
Q

Transamination

A

Reversible chemical reaction that transfers the amino group of an amino acid to a keto acid

34
Q

Keto acids

A

Resemble amino acids except that the second carbon binds to an oxygen atom rather than to an amino group

35
Q

Deamination

A

The amino groups is removed an an ammonium ion is released

Liver cells are the primary site

36
Q

Amination

A

An ammonium ion is used to form an amino group that is attached to a molecule, yielding amino acid

37
Q

Nonessential amino acids

A

Body can make them on demand

38
Q

Amination

A

Adding of an amino group

39
Q

Absorptive state

A

Energy storage
Time following a meal
4 hours
Insulin primary hormone

40
Q

Postabsorptive state

A

Energy release
When nutrients aren’t being absorbed
Glucagon, epinephrine, glucocorticoids, and GH

41
Q

Nitrogen balance

A

Difference between total nitrogen you consume and the amount you excrete

42
Q

Minerals

A

Inorganic ions