Muscle Flashcards
skeletal muscle structure
striated, long multinucleated peripheral nuclei, voluntary contraction, parallel fibers with no branching, sarcomere units defined by Z lines
cardiac muscle structure
striated, branched, round central mononuclear nuclei, intercalated disks mark units, forms the myocardium, has purkinjie fibers
smooth muscle structure
unstriated, looks similar to dense regular connective tissue, cells are spindle shaped with numerous central cigar shaped mononuclear nuclei
A band
dark staining thick band, thin filaments overlap thick filaments
H band
zone of pale staining in the center of the A band, no overlap
I band
zone of thin filaments that do not overlap thick filaments
Z line
dark band in the center of the I band, define sarcomeres
M line
line down the center of the H band
compare skeletal and smooth muscle
skeletal is striated with long multinuclear peripheral nuclei and parallel fibers, smooth is unstriated, looks similar to dense regular connective tissue, cells are spindle shaped with mononuclear cigar shaped nuclei
purkinjie fibers
usually occur in bundles and are part of the conducting system of the heart. they stain lighter due to increased glycogen, often found in groups of 2 or 3
sarcoplasm
muscle cell cytoplasm
sarcolemma
muscle cell membrane
sarcoplasmic reticulum
endoplasmic reticulum of muscle cells for transport, synthesis, storage, and packaging
actin
thin unit
myosin
thick unit
epimysium
surrounds the whole muscle
perimysium
subdivides muscle into bundles to form fascicles
satellite cells
resident population of muscle precursor cells, form new muscle cells after damage
accessory proteins
actinin, myomesin, connectin, desmin, C protein
actinin
holds actin filaments in a lattice arrancement in the Z disc
actinin
holds actin filaments in a lattice arrancement in the Z line
myomesin
hold myosin in a lattice arrangement in the M line
connectin
links ends of the tick filaments to the Z line
desmin
link myofibrils to the cell membrane and links adjacent myofibrils to each other
C protein
myosin binding protein
desmosomal junction
link adjacent cells with intermediate filament anchors
adherent junctions
anchors actin fibers of the sarcomere to each end of the cell
gap junctions
for communication and help synchronize muscle contraction
actinin
holds actin filaments in a lattice arrangement in the Z line