Mouth, Esophagus, Digestive Tract Flashcards
structure of the oral cavity
stratified squamous epithelium, lamina propria, salivary glands serous and mucous, skeletal muscle in deep layers, and filiform papillae on top layer of tongue
structure of taste buds
occur only on the sides of fungiform papillae scattered on the surface of the tongue, and rarely on the circumvallate papillae at the back of the tongue
egg shaped and consist of elongated sensory cells which extend from the lamina propria to the surface taste pore
also contains support cells and stem cells at the base
structure and function of the esophagus
hollow tube 25cm long, moves partially digested food from the pharynx to the stomach
four layers of the esophagus
mucosa (non keratinized stratified squamous epithelium)
submucosa (blood vessels, glands, and connective tissue)
muscularis externa (upper third is skeletal, lower third is smooth, middle is a mix)
adventitia (connective tissue that merges with connective tissue of surrounding structures)
characteristics of Barrett Esophagus
heartburn and chest pain
simple columnar epithelium replaces the stratified squamous epithelium to withstand stress
histologic changes at the Z-line of the gastroesophageal junction
abrupt transition from nonkeratinized stratified squamous to simple columnar epithelium
three nerve components of the ENS (enteric nervous system)
nerve fibers, ganglion cells, and glial cells
origin of the ENS
neural crest
two parts of the ENS
Auerbach plexus: larger myenteric plexus
lies between the inner and outer layers of smooth muscle in the muscularis externae
regulates contraction, peristalsis, and gastrointestinal mobility
Meissner plexus: regulates glandular secretion and local blood flow, innervates cells in the epithelium and smooth muscle of the muscularis mucosae
characteristics of hirschprung disease
absence of ganglion cells in the ENS, only nerves can be seen, not the normally present pink ganglia
uncoordinated peristalsis, constipation, and possible obstruction
four regions of the stomach
cardia (cardiac region near GE juntion), fundus (uppermost portion), body (majority), and pylorus (end near pyloric sphincter)
cells of the stomach
parietal cells, chief cells, enteroendocrine cells
three segments of the small intestine
duodenum: short, leaf shaped villi, enterocytes, and goblet cells
jejunum: tall, slender, finger-shaped villi
ileum: paneth cells are most numerous here, they regulate flora and produce lysozyme
segments of the large intestine
ileocecal junction, cecum, ascending colon, transverse colon, descending colon, sigmoid colon, rectum, and anus
function and location of goblet cells, paneth cells, and enterocytes
goblet cells increase towards colon, paneth cells dense in ileum, enterocytes line the lumen of small and large intestine